Intestinal bacterium involved in the development of type 1 diabetes

Were the NOD mice treated with the gut bacteria Parabacteroides distasonis colonized, this increased the development of diabetes. In addition, the researchers were able to detect antibodies directed against the bacterium in the colonized mice and also in type 1 diabetics. Finally, analysis of the gut microbiome data from children with an increased risk of type 1 diabetes from the »Diabimmune« study that Kinderin whose gut microbiome the epitope hprt4-18 was found, had two or more autoantibody types more frequently than Kinder without hprt4-18.