Isoliquiritigenin from Licorice: A Promising Treatment for Pancreatic Cancer

2023-08-23 04:00:03

Researchers have discovered that isoliquiritigenin (ISL), a flavonoid from licorice, can effectively fight against pancreatic cancer. This molecule seems to inhibit the progression of cancer and improves the effects of chemotherapy.
Image d’illustration Pixabay

cancer of the pancreas has the particularity of being often taken into charge late due to the absence of symptoms at its onset, having a direct impact on the survival rate. Scientists from theUniversité baptist of Hong Kong say they have found a solution to slow the progression of this cancer. The solution would be in a compound extracted from the licorice, called isoliquiritigenin. The results of this research were recently presented at the annual congress of the European Association of research sur le cancer 2023, and are published in the journal Phytomedicine.

Licorice is already widely used in traditional Chinese medicine because of its many health benefits. health. As part of their research, the scientists studied theensemble chemical compounds of licorice as well as markers specific to this type of cancer. After numerous experiments, they succeeded in isolating ISL and demonstrating that this flavonoid was able to inhibit the growth of pancreatic cancer cells and induce their mort programmed cell.

The tests carried out on mice are conclusive: the survival rate of cancer cells was very low compared to cells that had not been treated with ISL. In addition, the mice given the licorice compound showed significantly fewer side effects than the others. Combined with chemotherapy, this process is promising and gives hope to the many patients with this devastating cancer.

This article complements the recent news that we have already shared with you on pancreatic cancer, relating to a messenger RNA vaccine against this cancer (lien), or on a artificial intelligence able to predict the appearance of the latter (lien), but also on a medicine used in cardiology who would be able to cure itlien).

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