Karla Souza to Star in New Grey’s Anatomy Spin-off Series

Mexican actress Karla Souza will star as a cynical doctor leading a rural Texas medical center in the upcoming third spin-off of the long-running medical drama Grey’s Anatomy.

  • Rural health facilities like the one featured in the upcoming series often serve as the sole point of care for vast, isolated populations.
  • Medical dramas frequently dramatize triage protocols and resource scarcity, highlighting real-world challenges faced by healthcare providers in remote areas.

Karla Souza expressed her gratitude to followers on social media after securing the leading role in the upcoming ABC expansion. “Solo estoy tomando un momento para procesarlo todo y sentirme profundamente agradecida. Muchas gracias, chicos, por seguir conmigo y apoyar todo este viaje,” she wrote online, reflecting on the milestone.

Variety reported that Souza was cast as Dr. Carolina “Lina” Hall, described as a tormented and cynical physician directing a healthcare facility in western Texas. The project represents the third derivative in the franchise, following Private Practice and Station 19.

Grey’s Anatomy Texas Spinoff FINDS Its Meredith Grey Karla Souza Cast as Lead#fullepisode #today — Grey's Anatomy Official

Deadline described the upcoming series as an intense drama centered on a medical team operating in a remote regional center that serves as the final option for healthcare before an unpopulated expanse. Shonda Rhimes and Meg Marinis are developing the show as creators and executive producers, joined by Grey’s Anatomy lead actor Ellen Pompeo.

The premiere was originally planned for the 2026-2027 television schedule but was pushed back to the 2027-2028 cycle after the production failed to secure a California television tax credit. Souza’s previous credits with the network include Home Economics and How to Get Away With Murder.

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Priya Deshmukh - Senior Editor, Health

Priya Deshmukh Senior Editor, Health Deshmukh is a practicing physician and renowned medical journalist, honored for her investigative reporting on public health. She is dedicated to delivering accurate, evidence-based coverage on health, wellness, and medical innovations.

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