Dr. Moo Wirasak warns that taking paracetamol regularly increases the risk of cerebrovascular disease.
Tojo News reporters reported that Assoc. Prof. Dr. Wirasak Charoenchaisri, a forensic medicine specialist at Srinakharinwirot University, posted a message on Facebook stating that:
Regular use of paracetamol may increase the risk of stroke and heart disease by up to 20 percent.
Paracetamol was previously assumed to be a perfectly safe drug for patients with high blood pressure until recently.
A 2022 study found that long-term use of paracetamol may increase the risk of heart disease and stroke in people with high blood pressure.
The researchers say its effects on blood pressure are similar to those of nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen.
As part of a study conducted by a team from the University of Edinburgh, 110 patients with a history of high blood pressure were given either 1g of paracetamol (2 500mg tablets) four times a day (4g daily (8 500mg tablets daily)) or a matching placebo for two weeks.
The paracetamol group showed a significant increase in blood pressure compared to the placebo group.
This increase is similar to that seen with nonsteroidal anti-inflammatory drugs and could be expected to increase the risk of heart disease or stroke by about 20 percent.
Conclusion: Taking paracetamol for 2 weeks increases blood pressure in hypertensive patients, and when the drug is stopped, blood pressure returns to baseline.
Those who use paracetamol occasionally do not need to worry. Short-term use of paracetamol to treat headaches or fevers has no effect.
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