2023-05-17 08:30:00
A study published in the Journal of Clinical Investigation indicates that obesity-induced inflammation worsens clonal hematopoiesis of undetermined potential. The researchers discovered that this clonal hematopoiesis (CHIP), a common process in aging, causes an accumulation of genetic mutations in blood cells. This leads to an increased risk of developing blood cancer. The study also shows that obesity is a trigger for CHIP because it causes inflammation in the body and changes the bone marrow where blood cells are made.
Understanding the Effects of Obesity
The implications of this study are important for understanding the effects of obesity and the promotion of a healthy lifestyle on health. Findings suggest that finding ways to limit weight gain and control one’s level of systemic inflammation may reduce the risk of developing blood cancer as you age.
The researchers also tested different drug combinations to target CHIP mutant cells and find potential therapeutic approaches for the disease. Drugs commonly used to treat blood pressure and diabetes may play a role in regulating the growth of mutated blood cells.
Exercise and healthy lifestyle to prevent obesity
This established link between obesity and the blood disease CHIP which can, in the long term, increase the risk of blood cancer underlines the need to better fight against excessive weight gain. Apart from following a balanced diet, it is also important to exercise regularly and follow a healthy lifestyle to prevent disease.
Numerous studies have shown that people who follow a Mediterranean diet, which is high in vegetables, fruits and unsaturated fats, have a lower risk of developing blood cancer. Healthy living can also help reduce the risk of cardiovascular disease, diabetes and other chronic diseases also linked to obesity.
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