the wind changes direction
22 Feb 2022 07:00
number of infected people Covid-19 The omicron strain BA.2 increased rapidly. 20 Feb. 18,953 new cases, 8,814 ATK cases, total 27,767 cases, 30 deaths. Director of the Division of Epidemiology, Department of Disease Control, expects the peak of new infections around mid-March. This outbreak has spread to every group, every cluster, family, workplace, and friends. dining together It’s time to take off the mask. while the chance of infection from unknown people is almost nonexistent.
What I’m worried about is Songkran long break forthcoming If the government opens to enjoy Songkran as full as last year may see new peaks infected 4-5 thousand people per day
Dr. Anan Chongkaewwatana, virologist Director of Animal Health and Management Innovation Research Group The National Center for Genetic Engineering and Biotechnology (Biotech) posted the horror of Omikron Gen 2 (BA.2) from Japanese research saying: “As fierce as a delta”, Omikron BA.2 had approximately 30-40% more infective capacity than BA.1. A spike that is unique to himself Alterations elsewhere outside the spike protein are believed to have contributed to BA.2’s superior properties than BA.1.
There is the latest research from the Japanese team. It is the result of a vaccine immunization experiment from volunteers in Japan. When compared between omikron BA.1 and BA.2, it was found that BA.2 escaped immunity higher, for example, immunity from Moderna vaccine was 15 times escaped by BA.1, but BA.2 escaped 18 times, and Immunity from the Astra vaccine BA.1 escapes 17 times, but BA.2 escapes 24 times.
interesting is Immunity resulting from BA.1 omicron infection was also escaping by BA.2. Although the two viruses are believed to be the same omikron group. But the difference between the two strains made immunity from BA.1 escaped by BA.2 virus nearly three times. Results in mice that received a BA.1 spike-designed vaccine were exposed to BA.2. 6.4 times as many escapes, the two species of omikron may not be used as a vaccine interchangeably.
The research team believes that BA.2 may not be as omikron as BA.1, both with different viral properties. and differences in immune responses, this BA.2 virus may be renamed Pi, the next letter after Omicron
Dr. Anan continued to post on Sunday that Recent studies have shown that BA.2 is prone to resistance to almost all developing therapeutic antibodies. But the study results from natural infection and vaccination. make us believe There must also be antibodies that capture the omikron in our bodies, but it is very difficult to find and isolate those antibodies from pools that contain many other antibodies, and it takes a lot of luck.
The good news today is A team from the Netherlands found that an antibody isolated from one clone, 87G7, was able to pass through the omikron barrier BA.1 and BA.2, capturing the spike protein and blocking its entry into cells of the virus. The results of experiments in infected animals showed that it was very effective at preventing infection. An in-depth study found that antibody 87G7 binds to spikes at key strategic sites used to enter cells at six amino acid sites unchanged in all virus strains at this time. It could be a difficult point to change. If so, 87G7 is an antibody capable of suppressing all virus strains. If not mutated in these 6 amino acids
I would like to help you make it successful. will be able to stop the outbreak of this deadly virus.
“The wind changes direction”
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