Preventing Contraindicated Drug Interactions: Essential Information and Prevention Tools

2023-08-25 07:08:49

The aging of the population and the increased prevalence of chronic diseases in Western countries have led to an increase in the overall consumption of medicines. As a result, more and more people are on polypharmacy, a situation that exposes them to the risk of drug interactions.

The joint use of drugs whose combination is contraindicated can be the cause of very diverse interactions ranging from a decrease in the effectiveness of these molecules to adverse effects of variable intensity which can go as far as death. .

In the United States, a third party appeals annual hospitals would be linked to the occurrence of drug interactions, according to the US Department of Health and Human Services. In France, exposure to drug interactions that are theoretically contraindicated multiplies the risk of urgent hospitalization by nearly 2.5, which represents between 4,500 and 8,900 potentially avoidable urgent hospitalizations per year. These results confirm the need to strengthen the training of physicians in prescribing practices and to develop prevention tools to avoid contraindicated drug interactions.

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