Rare Case of Spreading Shingles: Symptoms, Treatment, and Prevention

2023-11-04 14:13:05

Dr. Manoon encountered a case of a patient suffering from the spread type of shingles. It is rare. Symptoms start with a fever and blisters on the body.

Tojo News reporter reported that Dr. Manoon Leechawengwong, a physician specializing in respiratory system diseases. Vichaiyut Hospital Posted a message via Facebook, Dr. Manoon Leechawengwong FC stated:

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Spreading type of shingles (Disseminated Herpes Zoster)

Found very rarely in healthy people. There are blisters and pustules all over the body. The virus can enter the bloodstream and travel to organs such as the lungs, liver and brain. Spreading shingles is treated with acyclovir intravenously.
The patient is a 50-year-old female, normally healthy. Had chicken pox as a child Became sick on October 15, 2023, had a fever, severe headache, body aches, and mouth sores for 3 days. Later, water blisters and pustules appeared on the skin, most on the earlobes on both sides, spreading to the forehead (see picture), chest, neck, back, and There were few bumps on both thighs, there were sores in the mouth, there was no history of being in close proximity or contact with people who had smallpox. Went to a nearby hospital on October 19 and received acyclovir intravenously for 2 days. Requested transfer to Vichaiyut Hospital for further treatment.

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Blood test found slight anemia. Liver enzyme values ​​were slightly elevated, SGOT 54, SGPT 43. Aspirated fluid from the pustules was tested for infection using the PCR genetic code method. No smallpox virus and Varicella zoster virus were found. Send blood for infection by the genetic code PCR method. Varicella zoster virus and virus were not found. Herpes simplex type 1, 2, after testing the cerebrospinal fluid, found 68 white blood cells, 81% of which were lymphocytes. Protein in the cerebrospinal fluid was slightly high, 49, sugar was normal, 56. Detection of infection in the cerebrospinal fluid by genetic code PCR did not find Varicella zoster virus. and Herpes simplex viruses type 1, 2
Conclusion: This patient is likely infected with Varicella zoster Virus (VZV), the shingles virus, which is the same virus as the chickenpox virus. Causes invasive shingles and meningitis. No infection was detected because the patient received acyclovir before coming to Vichaiyut Hospital to administer acyclovir intravenously. After giving medicine, the fever subsided. Headache improves Mouth sores improved The pustules dry up. Finally, if the scab develops, acyclovir will be injected into the vein continuously for 14 days.
Thailand currently has a highly effective vaccine that can prevent all forms of shingles.

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