Red ginseng helps suppress lung cancer metastases

Thanks to a microwave method, red ginseng would be able to fight against lung cancer metastases.

According to a new study, researchers at the Korea Institute of Science and Technology (KIST) found that two active compounds in red ginseng would be effective against lung cancer metastases. Specifically, Rk1 and Rg5 would have proven anti-cancer effects. The findings were published in the Journal of Ginseng Research.

Red ginseng has long been used as an ingredient in traditional Korean medicine. This new method of microwave treatment was developed by Dr. Jungyeob Ham, co-author of the study. This approach, called KMxG, is based on the same principle as the microwave oven. It increases the concentration of the three main active components Rg3, Rk1 and Rg5 more than 20 times.

The research team has previously shown that the red ginseng produced by this microwave treatment method is effective against cancers of the prostate, cervix and skin. It also has protective effects against drug-induced kidney damage.

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Towards new anticancer drugs

Although components in red ginseng have been shown to kill cancer cells, this study proved that these components in red ginseng have other anti-cancer effects and may inhibit lung cancer metastasis. This provides scientific evidence that could lead to the future development of anti-cancer, an anti-cancer drug derived from natural products.“Dr Ham remarked. Before adding:”Because we can control the active ingredient content of red ginseng using microwave processing methods like the one that produced KMxG, it may be possible to develop custom functional materials for various diseases.“.

Unlike normal cells which die when separated from their original tissue, cancer cells can spread to other tissues and invade them in a process called metastasis. In this study, the research team treated lung cancer cells with Rk1 and Rg5, the main components of KMxG red ginseng. Thus, it showed that the two components effectively inhibited various processes linked to cancer metastases induced by TGF-β1.

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