2023-05-09 05:45:59
Smoking, diabetes, chronic pancreatitis, genetics, and obesity are risk factors for pancreatic cancer.
Men who drink or smoke are more likely to develop cancer than women. However, the male to female ratio of pancreatic cancer patients is similar. A little too many men Of the 8,414 new patients in 2020, 4,324 were male and 4,090 were female. If you look at the ranking of women’s cancer, the ranking has changed from stomach cancer-lung cancer-liver cancer (2019) to lung cancer-stomach cancer-pancreatic cancer (2020). The number of female pancreatic cancer patients is on the rise.
◆ What is the most important risk factor for pancreatic cancer?
The most important risk factor for pancreatic cancer known to date is smoking. Cigarette smoking increases the relative risk of pancreatic cancer up to fivefold. About one-third of pancreatic cancer is caused by smoking (National Cancer Information Center). There is also a report that the incidence of pancreatic cancer increases when smoking-related head and neck cancer, lung cancer, and bladder cancer occur. Even if you quit smoking, your risk of getting pancreatic cancer is as low as that of a non-smoker after 10 years or more. The sooner you quit smoking, the better.
◆ Diabetes for a long time vs suddenly diagnosed with diabetes without a family history
Diabetes may be the cause of pancreatic cancer, but on the contrary, secondary endocrine dysfunction associated with pancreatic cancer is also considered to cause diabetes. There is a research report that people who have been suffering from diabetes for more than 5 years have an increased incidence of pancreatic cancer. On the other hand, diabetes usually develops 2 years before pancreatic cancer diagnosis, and if the cancer is removed through surgery, diabetes may improve within 3 months.
Therefore, people who have been suffering from diabetes for a long time and those who have been suddenly diagnosed with diabetes without a family history are advised to get tested for pancreatic cancer. The risk of developing pancreatic cancer in patients with type 2 diabetes is 1.8 times higher. The prevalence of diabetes among pancreatic cancer patients in Korea is 28-30%, more than three times the general population (7-9%).
◆ Drinking and enjoying chronic pancreatitis… Potential cause of pancreatic cancer
Chronic pancreatitis is a disease in which normal pancreatic cells become inflamed and the entire pancreas becomes very hard and loses its function. The most important cause is drinking. Since chronic pancreatitis increases the risk of pancreatic cancer, it is considered a causative disease of pancreatic cancer. In some cases, it is very difficult to differentiate between chronic pancreatitis and pancreatic cancer. Pancreatitis is not life-threatening, but cancer is a fatal disease, so a thorough differential diagnosis is necessary.
◆ Patients in the immediate family… Hereditary 10%, regular checkup required
Familial pancreatic cancer should be suspected if one or more immediate family members, such as parents, siblings, etc., had pancreatic cancer before the age of 50, or if there were more than one pancreatic cancer patient regardless of age. You should consult your doctor for regular check-ups. There is a case where pancreatic cancer occurred in one family over three generations. Genetic predisposition accounts for about 10% of the causes of pancreatic cancer. Mutations in a gene called K-Ras have been found in more than 90% of pancreatic cancers. It is the most common genetic abnormality in all cancers.
◆ What are your food and eating habits? Eat fruits and vegetables that are high in antioxidants
Recently, many studies have shown that food or eating habits affect the occurrence of pancreatic cancer. Excessive intake of meat-fat-carbohydrates and obesity due to excessive calorie intake increase the risk of pancreatic cancer, while fresh fruits and vegetables are reported to lower the risk. Therefore, it is good to reduce meat-centered high-fat-high-calorie foods and eat a lot of antioxidant-rich fruits and vegetables. Be especially careful with burnt meat as it can cause carcinogens. It is also necessary to maintain a healthy weight through exercise.
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