2024-03-22 05:51:00
▲ Scientists in the Netherlands have used “gene editing” technology to successfully eliminate the human immunodeficiency virus (AIDS virus, HIV) from infected cells.
[AIDS/HIV/Treatment/Gene Editing/Dawn of AIDS/HIV/Removal of Cancer Cell DNA/Radical Cure of AIDS]There may be new hope in treating AIDS! Recently, scientists in the Netherlands used “gene editing” technology to successfully eliminate the human immunodeficiency virus (AIDS virus, HIV) from infected cells. However, the research team emphasized that it is still in the proof-of-concept stage and will not have a cure for AIDS in the short term.
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according toBritish Broadcasting Corporation (BBC)According to reports, a research team from the University of Amsterdam in the Netherlands stated at the 34th European Society of Clinical Microbiology and Infectious Diseases (ECCMID) pre-conference held this week that they used the Nobel Prize-winning Crispr “gene editing” technology to By operating like “scissors”, it successfully cuts out the “bad stuff” (HIV) on the cell’s DNA, thereby rendering it inactive and preventing it from relapsing again.
The team stated that their future goal is to completely remove HIV from patients, but emphasized that the entire project is still in the “proof of concept” stage and is still far away from clinical testing. Further research is needed to obtain results, and Ensure the safety and effectiveness of surgery.
The report pointed out that this is not the first time that the medical community has tried this innovative treatment. In 2023, Excision BioTherapeutics, a biotechnology company headquartered in San Francisco, also used Crispr technology to successfully remove and destroy the HIV virus in three patients without major side effects.
In this regard, Jonathan Stoye, a virus expert at the Francis Crick Institute in London, said that although there have been some successful cases, considering the possibility of off-target effects (that is, Crispr did not edit the target as planned) genes, instead altering other genes), as well as long-term side effects, it remains “very challenging” to remove all HIV from the human body.
There is currently no drug to cure AIDS
According to information from the “AIDS Concern”, AIDS is an “acquired immune deficiency disease” caused by the “Human Immunodeficiency Virus” (HIV). HIV cannot directly cause symptoms, but after the virus enters the human body, it attacks the “T4 cells” (white blood cells and macrophages) in the human immune system, weakening the immune system and its ability to repair injuries on its own. At this time, some diseases that pose no threat to uninfected people, such as Pneumocystis pneumonia, can take advantage of the situation and cause infected people to become AIDS patients. Although there is still no drug that can cure the HIV virus, the treatments used in Hong Kong have greatly extended the lifespan of infected people.
The HIV virus exists in various body fluids of infected persons, including semen, blood, vaginal secretions and prostate secretions. An infected person can transmit the HIV virus to others through contact with these body fluids. The amount of virus present in saliva, sweat, tears and urine is extremely low and is not sufficient to cause infection. Since people infected with HIV may look the same as ordinary people, only an HIV antibody test can determine whether they are infected.
Once unfortunately infected with HIV, the infected person may experience the following symptoms:
Until now, the medical community has not yet completely cured AIDS, but there are many treatment methods that can reduce the level of viruses in the blood, thereby delaying the formation of AIDS and the invasion of other bacteria, and improving the health and quality of life of infected people. Hong Kong provides “cocktail therapy”, which can effectively suppress the HIV virus in the body. It inhibits the virus from attacking the immune system. Currently, as long as they follow the doctor’s instructions, most HIV-infected people can be cured within 3 days of taking the drug. Within 6 months, the virus in the body was successfully controlled and the HIV virus in the body was suppressed to an undetectable level. “Cocktail therapy” can successfully suppress the virus and prevent it from attacking the immune system. As long as the immune system is good, the infected person will not get “opportunistic infections”.
3 major causes of HIV infection
Among infectious diseases transmitted through blood, AIDS is the most dangerous. According to information from the Hong Kong Department of Health, AIDS is a variety of diseases caused by the gradual weakening of the immune system due to infection with the HIV virus. Causes include:
People with HIV may show no symptoms and look just like ordinary people. After a patient is infected with the HIV virus, the incubation period can reach 10 to 15 years. Over a long period of time, the patient’s immune system will be severely damaged and gradually lose the ability to resist serious diseases. Patients will suffer from rare “opportunistic infections” such as pneumonia and skin cancer, which will eventually lead to death.
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Editor in charge: Luo Jiaxin
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