2023-12-24 20:06:59
Given the development of technological applications of Artificial Intelligence (AI), sophisticated immunological therapies, along with new techniques to combat diseases, medicine is projected with hope for humanity, through eleven clinical trials on humans that the scientific journal Nature Medicine, has classified as determinants for 2024.
This series of trials range from new techniques with AI, to genetic editing, and stem cells that, when developed in the new year, could become a clinical reality with very good results.
One of these clinical trials has to do with the experimental drug called VERVE-101, a genetic editing that could be known as the first drug that edits the human genome within its own body.
It would be used to treat hypercholesterolemia or high cholesterol, where some mutations in the PCSK9 gene are involved, which would represent a great advance for patients with this disease.
In the case of AI, its contributions are aimed at the diagnosis of lung cancer. This study tests the technology to identify chest x-rays of patients who, after having a CT scan, on the same day, can know early whether they have or not lung cancer.
AI will also cover the area of patient triage through a clinical trial that will apply an Artificial Intelligence model to predict the risk of mortality among patients treated in emergency services, to establish the order and place in which they should be catered.
The Nature Medicine list includes a trial that plans to test whether screening for lung cancer every two years using CT scans equals the effectiveness of annual tests in preventing deaths in those who do not present abnormalities in their first medical examination.
For their part, patients with HIV could receive a T cell vaccine thanks to the study that will evaluate the safety and effectiveness of VIR-1388, designed for the prevention of this pathology that has claimed the lives of more than 40 million people in the world. world.
“This serum uses a cytomegalovirus vector to induce T cell immune responses against HIV acquisition,” Nature Medicine detailed.
In the area of mental health, by 2024, it is planned to carry out a clinical trial that will treat perinatal depression, a disorder that affects numerous mothers in the world before and immediately after childbirth.
In the case of children’s mental health, studies will be carried out on the abuse or neglect of fathers and mothers in any society; To this end, a randomized controlled trial will be carried out in which scientists will investigate the effectiveness and cost of an intervention model for the mental health of children between 0 and 5 years of age in foster care, evaluating how it translates into prognoses at two and a half years of age.
This will consist of providing care to patients during the second and third trimester of pregnancy with major depressive disorder.
Another novelty that clinical trials bring for 2024 is the use of embryonic stem cells to treat neurodegenerative diseases such as Parkinson’s, a disease that until 2019 affected more than 8.5 million people.
Immune therapies will be an essential part of treating patients with melanoma, one of the most common and serious types of cancer. To this end, it is planned to carry out a phase 3 clinical trial that will test a new adjuvant immunotherapy strategy against the current standard, to improve the effectiveness and safety of these techniques.
Medicine will also have important advances in terms of the malaria vaccine, since the long-term effectiveness of a serum in use, called R21, is being tested, and which uses characteristics similar to those that have been successful in vaccines such as that of the human papilloma.
The options to treat brain metastasis as a major complication of advanced breast cancer are minimal; However, by 2024 it is expected that the clinical trial of a drug will detect the HER2 protein, which is found at high levels in those who suffer from breast cancer.
International Agencies.
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