2024-04-02 16:37:20
High-intensity exercise has a protective effect that may not only slow but also reverse neurodegeneration in the brain in Parkinson’s disease. The benefits of physical activity were discovered by scientists at Yale University in the USA, who published an article in the journal npj Parkinson’s Disease.
10 people took part in the study. It turns out that high-intensity aerobic exercise helps preserve dopamine-producing neurons. After six months of exercise, the neurons became healthier and began producing stronger dopamine signals.
Parkinson’s disease is a neurodegenerative disease caused by the misfolding of the protein alpha-synuclein, which accumulates inside and damages dopamine neurons. A lack of dopamine causes symptoms such as tremors and slowness of movement.
The most common drug available, levodopa, replaces the missing dopamine. Although the drug is effective in relieving movement symptoms, it does not prevent ongoing neurodegeneration and may cause unwanted side effects with long-term use, such as uncontrolled excessive movement.
There is currently no cure for Parkinson’s disease.
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