Lack of sleep reduces the effectiveness of the flu vaccine by 50 percent, and doubles the risk of dying from COVID-19.
This is the result of a study at the University of California, Los Angeles (UCLA) School of Health Sciences. The study’s lead author, Michael Irwin, a psychiatrist and biobehavioral scientist at the UCLA School of Health Sciences, said: “If you don’t get enough sleep, you may be at increased risk of contracting infectious diseases, and some vaccinations may be less effective.” A small experimental study found that people who suffered partial sleep deprivation over the four days prior to getting the flu vaccine (a trivalent vaccine) had 50% lower antibody titers from the vaccine than those who had a normal sleep. Additionally, in healthy adults vaccinated against influenza and hepatitis, those who slept with shorter sleep durations had significantly lower adaptive immune responses and significantly lower clinical protection than those who slept normally. In particular, as a result of a recent study of more than 46,000 patients, COVID-19 patients with severe sleep disturbances were more than twice as likely to die from Corona as those who did not.
The research team also found that global warming could disrupt sleep and make you more vulnerable to infectious diseases such as the flu and COVID-19. A survey of 765,000 Americans also found that rising nighttime temperatures cause sleep deprivation, which has the greatest impact on low-income and elderly people during the summer months. According to the researchers, sleep helps prepare the body’s response to an injury or infection that may occur the next day. Sleep disturbance increases inflammation and reduces the body’s ability to fight infections. This may increase the risk of death in patients, including the elderly, who are at high risk of insomnia due to inflammatory disorders such as cardiovascular disease and depression. On the other hand, the longer the sleep time, the lower the bacterial load and the higher the survival rate in various infectious diseases.
The results of this study (Sleep disruption induces activation of inflammation and heightens risk for infectious disease: Role of impairments in thermoregulation and elevated ambient temperature) were published in the international scientific journal “Temperature” and Eurekalert) introduced.
By Kim Young-seop, staff reporter [email protected]
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