The combination of Sputnik V with Moderna or Pfizer “is effective and safe”: Unah

The combination of vaccines Sputnik V and Modern O Pfizer “it is effective and safe“According to a study by the National Autonomous University of Honduras (Unah), released this Tuesday, which was advised by the renowned Honduran scientist Salvador Moncada, who resides in London.



Sputnik-V


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Sputnik-V

“Preliminary immunogenicity results show an immune response equal to or greater than that achieved with conventional homologous schemes,” said Unah through its journal Presencia Universitaria.

He added that the increase in antibodies between the first and second doses was significant in the vaccinated participants, with laboratory evidence of natural SARS-CoV-2 infection, “and that” they presented a considerably higher immune response than those who had not been infected”.

According to the report, Unah led the study due to the need to find a solution to the lack of provision of the second dose of the Sputnik V vaccine, which will be applied to 40,000 Hondurans who were awaiting the arrival of the second component.



The finding suggests that people who have received the vaccine combination


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The finding suggests that people who have received the vaccine combination “may receive a third booster dose.” Photo: David Zalubowski, AP

The study was directed by the COVID-19 Committee of the Unah and the Department of Virology, accompanied by the Ministry of Health, the Honduran Red Cross and the advice of researcher Salvador Moncada.

The Honduran scientist Marco Tulio Medina indicated that “the data we have at this time highlights that this combination is safe and effective.”

He added that the finding suggests that people who have received the vaccine combination “may receive a third booster dose.”

The preliminary report emphasizes that “the prospective observational study of a case-control cohort evaluated the immunogenicity and reactogenicity of heterologous immunizations, first dose of the Sputnik V vaccine, followed by a booster with an mRNA-type vaccine (Moderna or Pfizer). , compared to homologous immunization ”.

“At 14 days there was a significant immune response and at 21 days a reduction in this response was observed, although it was always persistent and higher compared to day zero,” the study points out.



People who were interested in the study participated through a website, freely, voluntarily and with informed consent.  Photo: Rogelio V. Solis, AP


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People who were interested in the study participated through a website, freely, voluntarily and with informed consent. Photo: Rogelio V. Solis, AP

In addition, the report recalled that on July 29 the Unah received an official letter from the Ministry of Health confirming the approval of the research proposed by the University, to develop a scientific study on the crossing of Sputnik V and Pfizer or Moderna vaccines.

People who were interested in the study participated through a website, freely, voluntarily and with informed consent.

The COVID-19 pandemic, which began to spread in Honduras in March 2020, leaves at least 10,148 dead and 373,206 infected, the state-run National Risk Management System (Sinager) reported on Tuesday.

The Sinager report adds that since February around 6.4 million people have been vaccinated, of which 3.8 have received the first dose, and 2.4 million the two initially required by the health authorities.

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