2023-04-20 09:31:26
A healthy lifestyle is the best detox. While the consequences of an inefficient detoxification are multiple. Failure in Stage 1 will leave pollutants untreated. A phase 2 deficiency may lead to cell damage or mutations (cancerization): detoxification can, by itself, produce adverse health effects. Certain deficiencies (or excess), due to lack of intake (dietary mode), assimilation (intestinal balance), or excessive or compensatory use of nutrients (stress, exogenous or endogenous substances that requisition them, excessive sport, etc.), can disrupt this mechanism.
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Our detox capacities exceeded
Individual variations in enzymatic activity, unbalanced diet, excessive exposure to pollutants… the vulnerability factors of the detoxifying function are multiplying. This function has been shaped over millennia in response to the natural toxic substances it encountered, i.e. biopesticides that plants create for their own defense. They are very varied, so that the detoxification function is not very specific (about thirty enzymes for the three phases of detoxification) to be able to apply to tens of thousands of substances. During this evolution, the organism could only partially adapt to the industrial revolution. The 100,000 new synthetic substances that have appeared on the European market since that time were not foreseen either. The non-specific nature of the detoxification function makes it possible to support part of it, but it is also a drawback: the selective recognition of certain receptors can be deceived. For example, in the case of endocrine disruptors, the receptor of a cell thinks it recognizes a hormone and opens its door or its nucleus to it, whereas these are pollutants. There is a significant risk of error, and one can question the effectiveness of detoxification in such cases. This translates into a continual presence of substances of concern that can produce health effects before they are neutralized, with some pollutants themselves altering the detoxification mechanism. The body thus becomes less and less “competent” in this function.
Other functional aspects to consider
Repeated stress, poor sleep, sedentary lifestyle, poorly managed emotionsetc., disturb the physiology so that the detoxifying functions are not always prioritized. The autonomic system (adaptation to stress, microcirculation and priority of perfusion to muscles and brain) and biomechanical aspects (breathing, abdomen compressed by an inflexible diaphragm) mistreat physiology. Let’s learn to consider all of these elements in our detox process.
Strategy to improve detox
It is therefore likely that everyone can be affected by these shortcomings. The desire for “detox” is then founded, but the means and the promises remain to be debated. Besides, people who are polymedicated or very exposed to toxins deserve special care.
The Pr Robert Barouki, a biochemist and molecular biologist, speaks of a real race between the body’s elimination capacities and the contaminant’s nuisance capacities. If it is not possible to achieve zero exposure, the aim will be to reduce indoor exposure time (facilitate eliminations), while maintaining a balanced microbiota. This is to allow a faster and lasting result. The intentions of detox programs, the promise behind the notion of individualization, and the strategies are unfortunately not always appropriate.
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Detoxify, strengthen… assets for weaning
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