The Role of Vitamin B12 in Treating Ulcerative Colitis and Tissue Regeneration

2023-11-18 01:10:57

“Vitamin B12, helpful in treating ulcerative colitis”… It is also abundant in the liver and kidneys of cattle and pigs, and in salmon, tuna, and shellfish.

Entered 2023.11.18 10:10 Views 896 Entered 2023.11.18 10:10 Modified 2023.11.18 00:01 Views 896

Research results have shown that vitamin B12, which is abundant in egg yolks, can help treat ulcerative colon cancer. [사진=게티이미지뱅크]New research has shown that vitamin B12 plays a key role in cell reprogramming and tissue regeneration. In particular, it has been shown to be helpful in the treatment of ulcerative colitis.

The Barcelona Institute for Biomedical Research (IRB) in Spain announced that this new efficacy of vitamin B12 was proven in mouse experiments.

The research team focused on an experimental process called ‘cell reprogramming’, which is known to mimic the early stages of tissue repair. As a result, it was discovered that a large amount of vitamin B12 is used for cell reprogramming in mice. Vitamin B12 deficiency has been shown to slow and impair some aspects of the cellular reprogramming process. The research team emphasized, “Even a small amount of vitamin B12 supplementation significantly increases the efficiency of cell reprogramming.”

The research team specifically verified their findings in an ulcerative colitis model. As a result, it was found that intestinal cells that entered the recovery stage benefited from vitamin B12 supplementation by going through a process similar to cell reprogramming.

Dr. Manuel Serrano, lead author of the study, said, “The DNA of cells entering the cell reprogramming or tissue regeneration (repair) stage requires a very high level of methylation reaction, so vitamin B12 supplementation is very important.” He emphasized, “Vitamin B12 may be particularly helpful in the treatment of ulcerative colitis.”

During cell reprogramming or tissue regeneration, a lack of vitamin B12 causes epigenetic changes, causing errors in the function of various genes. Therefore, supplementing vitamin B12 during this process corrects the imbalance, increases the fidelity of gene function, and improves the overall efficiency of cell reprogramming.

Vitamin B12 is known as a micronutrient that plays an essential role in maintaining nerve function, supporting red blood cell production, and promoting DNA synthesis. Vitamin B12 is found in large quantities in egg yolks, salmon, tuna, clams, beef, and organ meats (accessories) such as pork and cow liver and kidneys.

Recently, a research team led by Dr. Serrano, in collaboration with the University of Barcelona (UB), also found that people with high levels of vitamin B12 in the blood have low levels of inflammatory markers (IL-6 and CRP). The research team said, “Vitamin B12 lowers inflammatory markers in the bodies of older mice, which means that vitamin B12 has an anti-inflammatory effect.”

The results of this study (Vitamin B12 emerges as key player during cellular reprogramming) were published in the international journal Nature Metabolism and introduced by the American health and medical media outlet MedicalXpress.

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