Surveys show that approximately 74% of Americans drink coffee daily. This puts America at the top of the list for the amount of coffee consumed worldwide. However, if we consider coffee consumption per person, the Scandinavian countries are well ahead, with more than four cups of coffee per day.
What makes coffee so popular? Whether it’s the taste, accessibility or appeal of caffeine, researchers are constantly working to find out whether a daily cup of coffee hurts or, conversely, helps. New study from the University of Tsukuba reveals that a delicious cup of coffee can do more than just give you a morning energy boost.
To study memory decline
Trigonelline (TG) is a natural substance found in coffee whose many health benefits have not yet been studied. This latest study reveals that TG may have beneficial effects on age-related memory decline.
This study involved two groups of mice, one injected with TG and the other without. They used the Morris water maze test to see if mice injected with TG could find their way around more easily than those who didn’t.
Study aimed to find TG benefits specifically in age-related memory decline. They therefore used mice with a natural predisposition to accelerated aging. The control group consisted of mice not predisposed to early aging. The study lasted 30 days, with TG injected daily into mice experiencing memory decline.
Morris Water Maze Test
The test performed in this experiment is widely used to study spatial memory and learning in animals. The maze takes place in a pool of opaque water and the animals are forced to find the escape platform without sight or smell. The test was developed in the 1980s and has been widely used to measure cognitive function and special memory.
Can trigonelline help with memory decline?
The study found that mice injected with TG found their way out of the maze almost as easily and quickly as mice not prone to early aging. This means that the mice did not experience the same memory decline as mice without TG.
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In the study, researchers were able to identify the targets of the neurotransmitter TG to have this memory effect. They discovered that the Traf6 transmitter is influenced by TG to interact with other transmitters, making it easier to solidify memories.
While these findings aren’t a comprehensive solution to memory decline, coffee drinkers may feel a little better about their morning cup of energy.
They also found that TG increases the levels of various neurotransmitters in the brain, making it easier to create new memories. It also has the benefit of solidifying long-term memories by increasing neurotransmitter levels.
These benefits were particularly visible in mice with memory decline. It could be very beneficial for people with Alzheimer’s disease and dementia. However, scientists maintain that there is still work to be done to consolidate these results and their use in the field.
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