Previously, scientists have found that these substances can disrupt the endocrine system and promote metabolic changes that can lead to steatosis – state when in liver tissues pathological changes begin due to excessive deposition of fat droplets in hepatocytes.
It is worth noting that in recent years, cases of steatosis are becoming more and more. If this ailment is not treated, it can come to steagepatitis, cirrhosis with all the ensuing consequences – up to liver failure.
During experiments involving mice, rats, frogs and primates, PFAS induced steatosis and lipid accumulation in animals. In addition, scientists were able to identify a link between exposure to chemicals and cholesterol level, triglycerides and uric acid are clear markers of metabolic disorders and liver diseases. However, it should be noted that transferring the results of studies to humans is not so easy due to the species characteristics and half-life of the chemicals listed above.
