Why hands and heart can be transplanted, but legs and stomach cannot be transplanted: immunologist explains

Arms are OK, but legs are not.

At the moment, there is evidence of successful transplants of whole limbs – hands that have taken root quite well and even work relatively tolerably. But with legs, because of their large size and other functional features, everything is more difficult.

  • Firstly, too large a zone of the body will be alien and the immune system will try in every possible way to reject the alien. It will need to be suppressed very seriously.

  • Secondly, transplantation will make sense only if the legs following engraftment are fully functional.

To date, attempts have been made, but no successful experiment has been reported. A transplant of even part of the legs – above the knee – by one of the surgeons in Spain, led to the rejection of both legs, and the grafts had to be removed. Therefore, a whole limb (and even more so both legs at once) in the pelvic area, it is unlikely that it will ever be possible to engraft.

Many people live without both legs, having lost them as a result of serious illnesses or accidents, disasters. Few of these unfortunate people will decide on such bold experiments, which also cost a lot of money.

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Alexandra Hartman Editor-in-Chief

Editor-in-Chief Prize-winning journalist with over 20 years of international news experience. Alexandra leads the editorial team, ensuring every story meets the highest standards of accuracy and journalistic integrity.

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