A Case Study on the Severe Vision Loss in an Iranian Man After Taking Sildenafil: Insights for the Academic World

2023-10-14 05:10:21

A 32-year-old Iranian man lost his right eye 3 hours after taking 100mg sildenafil… Reported to the academic world

Entered 2023.10.14 14:09 Views 10 Entered 2023.10.14 14:09 Modified 2023.10.14 14:35 Views 10

A case was reported of an Iranian man who lost his eyesight within 3 hours after taking an erectile dysfunction drug whose main ingredient was ‘sildenafil’. Left image = This is an image of an erectile dysfunction treatment and has nothing to do with a specific treatment.[이미지=게티이미지뱅크]. Right image = Damage caused by vascular occlusion in the right eye of a 32-year-old Iranian man.[이미지 출처_Journal of Medical Case Reports]The academic world is paying attention to the case of a 32-year-old man from Iran who lost vision in one eye after taking Viagra, an erectile dysfunction drug whose main ingredient is sildenafil.

According to foreign media reports such as the British daily Daily Mail on the 13th (local time), medical staff at the Farabi Eye Hospital in Tehran, Iran, published a report in the Journal of ‘Medical Case Reports’ was published last September. However, medical staff did not reveal when exactly this incident occurred. (Original report title_Central retinal vein and artery occlusion associated with sildenafil: a case report and review of the literature)

According to the report, the Iranian man suddenly lost his vision three hours after taking 100 mg of sildenafil. 100 mg is the maximum dosage for this drug and is twice the recommended amount for most men taking it for erectile dysfunction. The Iranian man went to the hospital because he could not see in his right eye after taking it, and told the doctor he had taken sildenafil. Despite the efforts of medical staff to restore his vision, the damage was so severe that he eventually lost his vision.

Sildenafil relaxes blood vessels, increasing blood flow to the penis and treating erectile dysfunction. This effect can actually harm other sensitive blood vessels in the body, such as the eyes.

Photo Caption_A. In the multicolor fundus photo of the blinded right eye, disc edema and extensive retinal hemorrhage are evident. Black arrows indicate macular folding due to severe retinal and optic disc edema. B (Normal Left Eye)The left eye had a normal cup-disc ratio. C, D. Images taken with indirect mobile funduscopy, inverted and inverted. Macular folding is visible (black arrow), and subretinal exudation is clearly visible in peripheral vision (red arrow). [이미지 출처_Journal of Medical Case Reports]After doctors examined the man’s eyes, they found he had suffered blood clots in the arteries and veins that transport blood to and from his right eye. This caused his retina, the light-sensitive tissue at the back of his eye, to swell. Macular edema, a condition in which blood leaks into the retina, also appeared.

Doctors reported that the pressure of this fluid appeared to have physically separated the retina from the rest of the eye. There were no other health problems in this man. However, because there were concerns about the risk of blood clots from the coronavirus vaccine and the virus itself, the medical staff also asked him if he had recently had an infection or received a vaccine. However, this man was not recently infected with the coronavirus and had not received any other vaccines.

What is unusual is that only the right eye was blinded, while the left eye was not damaged. Medical staff reported that there was no family history of blood clot problems that could explain the sudden damage to his eyes, and that the test results were negative, with no other underlying conditions diagnosed.

He went on to say that the man had eye and vision problems after taking sildenafil, but that more accurate research is needed on the relationship between the two. “Several serious retinal vascular accidents have been reported after using sildenafil, but the exact role of this drug is not clear,” the medical staff wrote in the report. “This patient’s case could be important data when discussing the relationship in future medical disease data.” “There will be,” he added. This is because there were no other medical conditions that could cause sudden blindness, such as underlying diseases or family history, and no causal relationship other than taking Viagra could be found.

“This patient was healthy and had no known risk factors for vascular disease,” the medical staff wrote. “Given the close temporal relationship that blindness developed immediately after taking sildenafil, we speculate that this drug may play a causative role in the clinical scenario.” Still, doctors acknowledged that the exact mechanism by which sildenafil could damage blood vessels in the eye was unknown.

One related theory is that sildenafil’s main effect is to increase blood flow to the genitals, which may increase the risk of inadvertently damaging the sensitive blood vessels in the eyes (if taken in large doses at once). How the drug interacts with the blood vessels in the eye may be more complex, the doctors added. They then requested further investigation into whether there is a potential link in young men taking Viagra.

The ‘little blue pill’ is best known as a treatment for erectile dysfunction, but it is also prescribed to patients suffering from pulmonary hypertension, which means dangerously high blood pressure in the blood vessels supplying the lungs. Sildenafil can be purchased without a prescription in the UK as a non-prescription drug. Reduction or loss of vision is listed as a potential rare side effect of sildenafil. In Korea, a prescription is required.

Meanwhile, earlier this year, Indian medical staff reported the case of a 41-year-old man who died from a stroke after taking a combination of erectile dysfunction medication and alcohol.

According to the UK’s National Health Service (NHS), only 1 in 1,000 people who take sildenafil experience serious side effects. If you take this medicine and experience side effects, you should stop taking it immediately and see a doctor.

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