The problem of pathogens

White ears is a fungus that can cause serious infections, especially in patients who are immunocompromised, who have pre-existing medical conditions, who are in long-term care facilities, or undergoing treatment with invasive medical devices such as a catheter. Infection prevention and control is difficult because the fungus can grow on dry and damp surfaces such as furniture, doorknobs, clothing, and medical equipment in healthcare settings. It has also shown resistance to many commonly used surface disinfectants and all three types of antifungal drugs. More than 1 in 3 patients with C. ear infections – which can affect the blood, heart or brain – die.

Additionally, Nevada, one of six states that have recently suffered heavy C. ear – last year, outbreaks broke out in multiple healthcare facilities and saw the highest number of fungal infection cases in the United States. The Silver State has seen a 16-fold increase, from just 24 cases in 2021 to 384 cases in 2022, according to the Centers for Disease Control and Prevention (CDC). Cases have also been reported in dozens of other countries.

what they found

A research team led by Casey Barber, a doctoral candidate at UNLV’s School of Public Health and a graduate intern at the Southern Nevada Water Authority (SNWA), recently published a study in the journal Environmental science and technology which analyzed 10 weeks of sewage samples from seven sewage ponds in southern Nevada.

Scientists have detected the genetic material of C. ear in at least one untreated wastewater sample from every wastewater treatment facility in southern Nevada and nearly 80% of all untreated wastewater samples in the study. Sewers serving healthcare facilities involved in the outbreak also showed higher detection frequencies for the fungus. The researchers noted that no fungi were detected in samples of untreated sewage from a sewage treatment facility in Utah, a region without C. ear case at the time. The fungus has not been detected in the Las Vegas Wash, which contains treated sewage effluent, or in Lake Mead, indicating that there are no signs that C. ear poses a risk to drinking water.

“These results show that wastewater monitoring can help monitor the spread of C. ear and might serve as an early warning system for public health action,” Barber said.

Other takeaways

The first human case of C. ear was reported in 2009, but has become more common in recent years. The fungus is often spread via contaminated surfaces or skin-to-skin contact with infected people, including those who are asymptomatic.

Scientists have called the Southern Nevada mushroom outbreak — which erupted in August 2021 and has now affected more than 30 healthcare facilities — one of the largest recent outbreaks of C. auris associated with state healthcare. -United. The research team officially launched C. ear-specific monitoring and data collection at the end of June 2022, as part of a larger ongoing collaboration on monitoring UNLV wastewater with SNWA.

In addition to the large-scale implications C. ear detection and prevention, the researchers said the study is groundbreaking in its progress toward establishing new procedures for the treatment, preparation and analysis of wastewater samples for research C. ear.

According to them, wastewater monitoring might provide a more accurate estimate of C. ear prevalence than traditional methods of public health surveillance, in part because traditional methods may not accurately identify C. ear leading to delays in targeted response measures. The team also anticipates that their previously established approach to monitoring levels of COVID-19 in wastewater might be applied to monitoring mutations and new strains of C. ear.

“Detection of White ears through sewage monitoring has already prompted expanded screenings in southern Nevada healthcare facilities in an effort to prevent larger outbreaks,” said SNWA Senior Research Microbiologist Daniel Gerrity. “This demonstrates how wastewater monitoring can be applied to emerging public health threats beyond COVID-19.

The hype is mounting around the versatile and very successful Eduardo Camavinga at Real Madrid, where the French international has established himself as a starter in the eyes of Carlo Ancelotti.

Replacing under the orders of the Italian coach last season, Eduardo Camavinga took his troubles patiently and it took him great good. The former Stade Rennais defensive midfielder is now a starter in the mind of Carlo Ancelotti at Real Madrid, sometimes as a left-back like once morest FC Barcelona this week or more often as a sentry in front of the defense, the position he love the most. Under contract with the club from the Spanish capital until June 2027, “Cama” left to stay for very long years at Real Madrid.

Eduardo Camavinga will extend to Real Madrid

But president Florentino Pérez remains on his guard and in order to ensure Camavinga’s presence at the club for as long as possible, he wants to offer him a contract extension according to information from COPE. The radio announces that Real Madrid will offer Eduardo Camavinga a contract extension until June 2029, with a salary increased for the occasion… and a new release clause. Currently, the release clause of the former Rennais amounts to 700 million euros, an already monstrous sum.

But this will increase to the tune of one billion euros, a good way for Florentino Pérez to protect his 21-year-old player and to ensure that no club will come to pay such an amount to recruit him short or long. middle term. The radio also reveals that if the staff of Real Madrid suddenly activated to upgrade and extend Eduardo Camavinga, it is partly because during the last winter transfer window, several English clubs including Manchester United or Chelsea demonstrated keen interest in recruiting him. However, it is simply impossible for Real Madrid to imagine the future without Eduardo Camavinga, who is well on his way to settling in the Spanish capital for a long time, before – no doubt – doing the same in the French team.