Dr. Anan reveals the research. Expected if high-risk groups get vaccinated. even if it does not prevent infection but can reduce the severity of smallpox
On August 7, reporters reported that Dr. Anan Chongkaewwatana, Researcher in Virology, Biotech Post messages via facebook Anan Jongkaewwattana It states that “high-risk people coming into contact with monkeypox patients It is believed that vaccinations can be followed later. Although it may not help prevent infection. but can reduce the severity of the disease The latest information from France came out interesting The data were collected from 276 high-risk people, most of which were through aerosol exposure (91%) or indirect contact that did not directly touch the patient, such as touching objects used by the patient or (71%). and exposure through unprotected sexual activity (54%). The % value will be redundant. Because the respondents thought that there could be more than one exposure to the virus, all high-risk people were vaccinated approximately 11 days after the risk day (8 days at the earliest and 14 days at the latest). All vaccinated still have no symptoms. The vaccine given to people at high risk is JYNNEOS (MVA-BN) Vaccine (IMVANEX, IMVAMUNE), which is an injection. It’s not the old version that is a vaccination.
Of the high-risk people who received the vaccine, 12 were diagnosed with monkey pox infection. (out of the incubation period), of which 3 were found infected 1 day after vaccination, and 1 were found on the 2nd and 3rd day, the other 5 were those who were detected 4-5 days after vaccination and had 2 people, the symptoms are quite late, that is, 22-25 days after receiving the vaccine, the data also indicates that 1 patient (Patient #6) was infected by collecting samples from patients and accidentally touched a contaminated needle. direct virus After being stabbed with a needle, he was immediately vaccinated. but found an infection four days later.
Of the 12 people who were vaccinated after the vaccine, 50% still had blisters and other symptoms such as fever, enlarged lymph nodes, sore throat, but overall symptoms were less severe than those in monkeypox patients in general. The research team believes that Vaccination after high-risk exposure, although it may not prevent 100% of infection, is likely to reduce the severity of the disease.
Unfortunately, from this study, there were no figures indicating that How many % of people who have been exposed to high risk who are not vaccinated will be detected? (How much more than 12 out of 276 people?) If there is this number, it will help to see the importance of using the vaccine in people who are at risk of coming into contact with those who are at high risk. get sick better