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Endurance sport against cancer
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![Do endurance sports to limit the risk of recurrence]()
Do endurance sports to limit the risk of recurrence
Do endurance sports to limit the risk of recurrence
Doing endurance would make it possible to run faster than cancer? Intense exercise increases the use of glucose by the muscles, which thwarts the formation of metastases. Result: the probability of a very metastatic cancer is considerably reduced.
This is revealed a study published in the journal Cancer Research (1), in which 3,000 people initially diagnosed with cancer were followed for twenty years. Participants who practiced regularly aerobic physical activity (which increases oxygen consumption and heart rate) of high intensity, such as running, cycling, swimming, football, cross-country skiing, have seen their risk of developing metastatic cancer decrease by 72% compared to sedentary people.
The sugar is the achilles heel of cancer. Cancerous tissues need it to grow and they tend to grab it. But they could have a major competitor: the muscles, which are particularly hungry for sugar during physical exercise. Aerobic physical exercise, provided that sugar intake has already been limited, allows muscles to consume much more glucose to the detriment of cancer cells, which then lack the fuel to proliferate.
In an attempt to explain the mechanisms, the researchers studied the phenomenon on animal models of cancer. Analysis of the metabolism of the internal organs of mice tells us that physical exercise stimulates glucose uptake, mitochondrial activity and expression of GLUT4 receptors. These facilitate glucose uptake by the muscles mobilized but also not mobilized by the exercise. Human plasma analyzes in regularly active individuals have also demonstrated increased carbohydrate utilization after exercise.
So far, many studies have shown that physical exercise reduces the development and recurrence of different cancers (2), including the most common. Recently, dissemination of metastases has been suspected to occur via circulating mitochondria. However, the use of glucose by our cells and the functioning of the mitochondria are closely dependent. We now know that exercise protects against the spread of cancer by reducing nutrient availability to tumor cells. Sport therefore seems to be, along with diet, one of the two main tools at our disposal to prevent cancer.
Read also
Cancer: reduce the risk by 35% thanks to sport
Bibliographic references 
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