Erythritol and Platelet Aggregation: Study Finds Link to Increased Risk of Heart Disease and Stroke

2023-04-15 07:18:00

The 2023 study found that erythritol, a polyol, speeds up platelet aggregation. Until increasing the risk of clogged arteries

The study began as an un targeted metabolomics study in 1157 people who assessed cardiovascular risk (discovery cohort) by undergoing coronary artery catheterization. They found that polyol levels, especially erythritol, were associated with increased heart disease and stroke after three years of follow-up. from the examination with GC-MS, but it can be said roughly and still cannot be linked to a clear level of quantity

A subsequent study specifically targeted metabolomics 2149 Americans and 833 Europeans (validation cohort) who assessed the risk of heart disease. The severity and follow-up data were available several years earlier. Using the blood samples of Americans from the 2013 report and merging them with those of Europeans. There was a clear association between erythritol levels and an increased risk. LC-MS (fourth versus first quartile adjusted hazard ratio (95% confidence interval), 1.80 (1.18-2.77) and 2.21 (1.20-4.07), respecti vely) and platelet function test showed increased stimulation both in vitro and increased atherosclerosis in rats

A follow-up study (intervention study) was specific in which 8 volunteers ingested 30 grams of regular-sized erythritol in a soft drink or keto ice cream. found high blood levels Floated until the next two days.

However, in food products that are commonly found There will be more than 30 grams of erythritol in a high dose to add more sweetness. The exact amount may not be specified because it is considered a safe substance.

The results of this report may need to be investigated. Increased rational relationship Although the experiment in This work will have results in studies in mice as well as in volunteers. Although there are as few as 8 cases, the platelet test shows a higher level of reaction that can cause damage to blood vessels.

The research team has identified issues that should be addressed from now on. The reason for this is that products should list the amount of erythritol. This may be as a standalone ingredient or in combination with natural substances such as Monk fruit, Hang Guo and Strevia, a stevia plant. It is 200 to 400 times sweeter than sugar, and erythritol may be added to many products to facilitate the production of ready-to-eat products.

But will wait for changes or changes in the future from this February 2023 data, which does not know how many months or years will have to wait.

Should or not that consumers may have to prepare themselves to choose more natural products? However, the sweetness from fruits and vegetables that must be eaten in the form of fiber as well into pieces without squeezing only the water and leaving the fiber out in this form The sweetness is safe and although erythri tol is synthetic It grows naturally in the body (endogenous), but the amount that occurs is less or less. Doses that have a stimulating effect and cause considerable damage to blood vessels.

the need to get close to nature Get closer to vegetarianism, reduce starch, meat, replace with fish, and avoid contamination with chemicals and substitutes. To maintain good health and not be a burden on oneself, family, society and the country.