2024-03-06 23:00:00
Home > News > How the maternal intestinal microbiota communicates with the fetus written on March 7, 2024 at 12:00 a.m. Article published in journal n° 121
Is amniotic fluid only used to protect the baby from external influences? Nothing is less sure. Researchers have just demonstrated that it contains millions of tiny vesicles secreted by bacteria from the maternal intestinal microbiota1. Ingested by the fetus, they would allowexpose its immature digestive tract to bacterial material, and thus prepare it, early, to be in contact with friendly bacteria which will colonize it at birth to form its future microbiota. To prove that these minivesicles were capable of crossing the placental barrier, scientists injected them into the blood of pregnant mice and showed that they were indeed found in amniotic fluid. Another study showed that in fetuses from mice without microbiota, genes involved in immunity were less active at the intestinal level, as were those involved in the development of the nervous system, in the functioning of the placenta or in energy metabolism2 . New evidence that the maternal microbiota communicates with the fetus and plays a fundamental role in its development.
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