“HPV Vaccination in France: Understanding the Two Injection Schedule for Adolescents and Catch-Up Options”

2023-05-12 17:00:00

While the WHO recently recommended that young people should only be vaccinated with a single dose to protect them from cancerous lesions caused by the papillomavirus (or HPV), the French Society of Colposcopy and Cervico Vaginal Pathology (SFCPCV) recalls that this scheme is not yet current in France.

Two injections 6 months apart

In December 2022, the World Health Organization (WHO) updated its recommendations concerning the fight against human papillomavirus (HPV), specifying that the single-dose vaccination schedule could offer efficacy and duration of protection comparable to a at two doses. “This limitation of HPV vaccination to a single dose would make it possible to increase the coverage rate which is still too low in the world and has even tended to decrease in recent years, going from 25% to 15% of the target population between 2019 and 2021”, explain the members of the SFCPCV in a press release. “This simplification of the one-dose vaccination schedule would also reduce its cost”, they add.

Nevertheless, health professionals point out that in France, anti-HPV vaccination remains recommended and reimbursed between 11 and 14 years old with two injections 6 months apart, and that a catch-up is also possible between 15 and 19 years old. gone with three bites. “For men who have sex with men (MSM), HPV vaccination is recommended and reimbursed up to the age of 26 with 3 injections”, continues the learned society. “We specify that any new vaccination must be initiated with Gardasil 9®”, add the members of the SFCPCV.

Systematic injection to adolescents

The classic vaccination schedule remains relevant in France for the moment “because it is the one with which the prevention of cancerous lesions of the cervix has been demonstrated (-88% risk if l’injection is made before the age of 17), anogenital lesions and lesions of the ENT sphere in men and women, and this without serious side effects, whether in terms of autoimmune, neurological, vascular, or in terms of premature ovarian failure”, conclude public health experts.

Although vaccination coverage against the papillomavirus is still low in France (only 41.5% of girls and 8.5% of boys have currently received two doses at age 16), the SFCPCV nevertheless thinks that the systematic offer of an injection to teenagers entering 5th grade will improve these figures.

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