2024-01-14 00:07:34
Diabetes increases heart disease risk through ‘inflammation’… Particularly dangerous in middle age when the aging process is accelerating.
Entered 2024.01.14 09:05 Views 2 Entered 2024.01.14 09:05 Modified 2024.01.14 03:22 Views 2
As you reach middle age, you have more thoughts and more stress. Stress affects the development of diabetes and heart disease through inflammation.
The link is metabolic syndrome. [사진=게티이미지뱅크]Research results have shown that stress can be an important cause of metabolic syndrome through inflammation.
A research team at Ohio State University in the United States found that stress is related to metabolic syndrome and that about 62% of the association was due to inflammation caused by stress.
People with metabolic syndrome have an increased risk of diabetes and heart disease. If you have three or more of the five conditions, including excessive belly fat (abdominal fat), high blood pressure, low HDL cholesterol (good cholesterol), high fasting blood sugar, and high blood neutral fat (triglycerides), it is called metabolic syndrome (insulin resistance syndrome). Genetics, lifestyle habits, and various internal and external factors affect metabolic syndrome.
“Stress influences the development of metabolic syndrome through the body’s propensity to cause inflammation,” said Jasmit Hayes, associate professor of psychology and lead author of the study. “Stress is especially harmful to health after middle age when aging accelerates,” he said. He emphasized, “If we manage stress, which is a psychological risk, well, we can reduce biological risk.”
The research team used data from 648 people (average age 52 years) who participated in a national survey titled ‘America’s Middle Ages’ to build a statistical model to measure the relationship between inflammation, stress, and metabolic syndrome. In addition, information such as perceived stress reported by respondents, blood biomarkers for inflammation, and physical examination results indicating risk factors for metabolic syndrome were used in the analysis.
To calculate the score that measures inflammation, the research team used biological substances such as interleukin 6 (IL-6), C-reactive protein, E-selectin and ICAM-1, which help recruit white blood cells during inflammation, and fibrinogen, a protein essential for the formation of blood clots. A marker was used. Studies have shown that stress is in fact closely related to metabolic syndrome, and statistical modeling has shown that inflammation explains 61.5% of the association.
“The link between stress and biological health is well-established,” said Savanna Jurgens, a graduate student and first author of the study. “However, there have been few studies that have specifically looked at the involvement of inflammation in the link between stress and metabolic syndrome,” she said. There are many studies showing that stress is related to inflammation, that inflammation is related to metabolic syndrome, and that stress is related to metabolic syndrome. However, research results that comprehensively examine these three variables are rare.
Factors that have a negative impact on health include stress, lack of physical activity such as exercise, unhealthy eating habits, smoking, lack of sleep, low socioeconomic status, old age, and being female. Associate Professor Hayes said,Stress should not be thought of as just a mental health problem, that is, a psychological problem. Chronic Stress Really Affects Your Body“He called attention. The research team said that research that goes beyond observational studies and directly proves causal relationships is needed.
The results of this study (Inflammatory biomarkers link perceived stress with metabolic dysregulation) were published in the journal Brain, Behavior & Immunity–Health.
Reporter Kim Young-seop
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