2024-02-13 14:59:00
Neuroimmunologists from Germany and the UK conducted a study that revealed new aspects of the interaction between the skull and the brain, which have important implications for understanding and treating inflammatory processes in the brain.
They discovered that there is a connection between the bone marrow of the skull and the meninges through which immune cells travel, promoting inflammation.
Experiments involving tissue clearing and 3D imaging allowed scientists to observe the close proximity of the cellular architecture of the skull and meninges. This discovery led to the conclusion that the connection between the skull and the brain is more complex than previously thought, Cell reports.
The researchers also looked at immune cells from different parts of the skull and found that they had unique molecular profiles, indicating diversity in the immune response in different areas of the skull.
Additionally, the study revealed changes in the skull of patients with Alzheimer’s disease and stroke, which may be key to developing better methods for monitoring and early diagnosing these diseases. The results obtained may have significant implications for the development of new approaches to the prevention and treatment of these neurological disorders.
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