PM2.5 and Osteoporosis: Research Findings from Mahidol University

2024-01-31 23:02:48

Calcium and Bone Research Unit (COCAB – Center of Calcium and Bone Research), Faculty of Science Mahidol University discovered that PM 2.5 increased the risk of osteoporosis from inflammation in laboratory rats.

1 Feb. 2024 Professor Dr. Narattaphon Phutthaphan, Director of the Institute of Molecular Biosciences Mahidol University Head of Calcium and Bone Research Unit (COCAB – Center of Calcium and Bone Research), Faculty of Science Mahidol University

Assistant Professor Dr. Natthaphon Panupintu, Head of the Laboratory Animal Research Unit, Faculty of Science Mahidol University

While PM2.5 covers the world, it not only affects the environment. But it affects humans and animals. Especially in the area of ​​health that threatens to cause various diseases

Including the risk of osteoporosis from inflammation throughout the body. Discovered from research on laboratory rats by the Calcium and Bone Research Unit (COCAB – Center of Calcium and Bone Research), Faculty of Science. Mahidol University which consists of quality researchers from the Department of Physiology who have participated in research studies to seriously, continuously and for a long time improve the quality of life of Thai people and keep them away from osteoporosis.

Professor Dr. Narattaphon Phutthaphan, Director of the Institute of Molecular Biosciences Mahidol University The head of the COCAB research unit collaborated with Assistant Professor Dr. Natthaphon Panupintu, head of the Laboratory Animal Research Unit, Faculty of Science. Mahidol University Research was conducted until it was discovered that PM2.5 risks osteoporosis. from inflammation in laboratory mice

Under the assumption that the mechanism of osteoporosis is from the deterioration of bone mass. There is an important cause of inflammation. This is because cells in the immune system must fight against PM2.5 dust that enters through the lungs and spreads throughout the body. To accelerate the inflammatory process. Following up on rats exposed to PM2.5 dust, an increase in the number of bone-breaking cells was found. which are cells that originate from certain types of white blood cells It plays an important role in the continuous decrease in bone mass. Risk of osteoporosis

PM2.5 dust that is threatening human health has different components in each area. Both in urban areas with heavy traffic and open areas where there is burning Dust itself may contain particles of a variety of chemicals. That is also harmful to health. PM2.5 dust not only enters the body through the lungs. But can also pass through the skin. and the digestive tract Many components in dust can also cause other chronic diseases, such as lung disease and metabolic diseases. even more severe

The discovery of the dangers of PM2.5 dust to bones is currently being submitted for publication in an international academic journal. To expand the results to find ways to prevent and treat To reduce the risk of osteoporosis and severe inflammation from the PM2.5 crisis that the world is facing in order to be “wisdom of the land” according to the aspiration of Mahidol University. Continue to increase surveillance.

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