“We believe that the initial fructose-dependent slowdown in brain metabolism was reversible and should have been beneficial. But the chronic and persistent decline in cerebral metabolism caused by repetitive fructose metabolism leads to progressive brain atrophy and loss of neurons, and then to Alzheimer’s disease – ScienceAlert words by Richard Johnson, nephrologist at the University of Colorado Anschutz Medical Center.
According to Johnson, experiments with lab rats show that if you keep them on fructose for a long time, tau and beta-amyloid proteins accumulate in their brains – the same ones that are observed in Alzheimer’s disease. Also, as the scientist notes, high levels of fructose in the brain can be found in people already suffering from Alzheimer’s disease.
The researchers now want to conduct dietary and pharmacological experiments to reduce the effects of fructose on the brain to determine if there is a potential benefit in preventing and treating the condition.
