Pregnancy and Biological Aging: Effects, Research, and Recovery – Latest Updates

2024-04-09 16:35:00
On October 10, 2022, Pregnant Women’s Day, seats for pregnant women are provided on subway line 1 trains operating in downtown Seoul. The photo is not directly related to the article. /News 1

A new study has found that pregnancy may actually accelerate biological aging in women.

According to the Washington Post on the 8th (local time), researchers at the Center on Aging at Columbia University in New York, USA, announced the results of a study showing that women who have experienced pregnancy are biologically older than women who have not, and that aging is even more accelerated in women who have had multiple pregnancies. did. This was published in the latest issue of the scientific journal Proceedings of the National Academy of Sciences (PNAS).

Researchers examined the pregnancy history and DNA samples of 1,735 women and men aged 20 to 22 in the Philippines. The biological age of the experiment participants was calculated using the ‘epigenetic clock’, a genetic tool for estimating biological age. The analysis showed that women who had experienced pregnancy experienced accelerated aging in all six epigenetic clocks compared to women who had not. Pregnancy included all pregnancies that resulted in miscarriage, stillbirth, and live birth.

This was valid even when controlling for other factors that affect the speed of biological aging, such as socioeconomic status, smoking history, and genetic risk factors. The researchers also found that women who had more pregnancies aged more quickly than women who had fewer pregnancies. In men, the number of pregnancies did not appear to affect the epigenetic clock.

“Our findings suggest that pregnancy accelerates biological aging and that this effect is evident in young, high-parity women,” said Callan Ryan, a researcher at Columbia University’s Center on Aging. There is still a lot to discover about it. “Also, it is unknown whether biological aging will affect health or death decades later.”

However, another study found that although pregnancy accelerates aging, there are also signs that these changes are reversed after pregnancy, especially when the mother breastfeeds. Recently, a research team at the Yale School of Medicine Child Study Center (YCSC) found that pregnancy increases biological age by 1 to 2 years, but the rate of aging decreases by 16% three months postpartum. Lead author and Assistant Professor Kieran O’Donnell said, “It is true that pregnancy accelerates aging, but there is a clear and distinct recovery after childbirth.”

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