Preventing Cervical Cancer: Screening and Self-Sampling with Associate Professor Dr. Wichai Termrungruanglert

2024-01-10 07:30:38

Associate Professor Dr. Wichai Termrungruanglert

Cervical cancer is a cancer that is commonly found in women from young adulthood to old age. and is the fifth most common form of cancer in Thai women. But at the same time, this type of cancer has a way to prevent up to 80 percent if you are regularly screened for human papillomavirus (HPV), which is the main cause of cervical cancer.

At present, the government sector has integrated cooperation with the private sector in campaigning for women at risk to undergo HPV screening by adding a self-sampling screening option, namely “HPV DNA Self-sampling or HPV DNA Test ” allows for self-collection of samples. To solve the problem of being embarrassed by doctors Afraid of getting on the trestle, afraid of getting hurt on the occasion of January. It’s a month for cancer organizations around the world. Join together to campaign against cervical cancer. To campaign for women to be aware of the importance of screening. as well as supporting the government sector in seeking ways to continually develop cervical cancer screening. According to the goal of eliminating cervical cancer to zero in the end.

The Roche Diagnostics (Thailand) Company Limited therefore organized a small seminar. In the topic of overview of cervical cancer screening using self-sampling “HPV DNA Self-Sampling with the next step in screening for cervical cancer in women” by Assoc. Prof. Dr. Wichai Termrungruanglert Department of Obstetrics and Gynecology Faculty of Medicine Chulalongkorn University

Demonstration of testing with HVP DNA Test

Associate Professor Dr. Wichai said that originally it was cervical cancer. It has been the number 1 cancer in women for a long time. Until now, breast cancer has taken the number 1 spot. Breast cancer has 22,000 new cases per year, with an average death rate of 8,000 people. Cervical cancer has an average of 9,000 new cases per year. year, or approximately 25 people per day, and has a death rate of up to 50 percent, or 13 people die per day, which on average, cervical cancer has a higher death rate than breast cancer. and compared to foreign countries The rate of cervical cancer is next or rarely found.

Associate Professor Dr. Wichai explained that cervical cancer is caused by infection with the HPV virus, which has many strains. There are 14 main cancer-causing strains, but the strain that is the real culprit is strain 16. and 18 is the cause of 70% of cervical cancers, which mostly occurs among young women between the ages of 30-40. Therefore, anyone who is tested for HPV has a higher chance of getting cervical cancer than women who are not. 35 times more likely to be infected with HPV. Infection with this virus may be found on toilet fixtures, stair railings, and door locks, but don’t worry if you clean your hands regularly. But the chance of finding infection is as high as 99 percent is through sexual intercourse. And men can get infected with this virus and cause cancer as well, such as anal cancer, penile cancer, oropharyngeal cancer, which throat cancer is caused by oral sex. When having sex, you should wear a condom.

“The time from the virus to developing into cervical cancer cells takes approximately 10-15 years, which is a slow incubation period for cells. And in the early stages, you usually don’t experience any symptoms. Therefore, this is a good time to get screened as a precaution. Because this type of cancer is considered one of the two cancers that can be prevented. By injecting the HPV vaccine, which in Thailand has 3 types: 2 strains, 4 strains, and 9 strains. All 3 doses must be injected, spaced apart from the first dose. To inject the 2nd dose approximately 2 months and inject the 3rd dose in the 6th month after injecting the 2nd dose, which is effective in creating immunity for up to 20-30 years,” Assoc. Prof. Dr. Wichai said.

HPV DNA Test Kit

Another best way to prevent cervical cancer is screening. Assoc. Prof. Dr. Wichai said that currently there are 2 methods of screening: 1. PAP Smear examination is a cytological examination. The doctor will collect a sample from the mouth area. to send for further examination in the laboratory and must be inspected annually which has an accuracy of 50-60% and a sensitivity of 53% for detecting disease when using the HPV DNA Test. It uses new technology to test at the DNA level to find high-risk HPV types, namely type 16 and 18 to find cancer risk or pre-cancerous conditions Those who wish to check can do so themselves. Just insert the swab deep into your vagina. Rotate the swab for 10-30 seconds and place in the sample tube. Similar to the COVID-19 screening method. With a swap through the nose and continuously inspect every 5 years

“This method was found to be 96% accurate and 92% sensitive in detecting the disease. Caution is that there must be no internal examination in the past 24 hours, no use of tampons or medicine used intravaginally. Give birth Do not wash or clean your vagina and refrain from having sex within 48 hours. Do not test during menstruation. In private hospitals, both methods are used to test together, which will make it accurate to 100%. But when comparing the efficiency of disease detection. Using the HPV DNA Test method is sufficient.” Assoc. Prof. Dr. Wichai confirmed the efficiency of the HPV DNA Test.

This is from statistics on cervical cancer screening among Thai women last year. 2020-2022 found that more than 5 million people have been screened by doctors, detecting strains 16 and 18 on average 1.5%, other strains 4.6%, while self-examination using the HPV DNA Test has over 80,000 people checked. Strains 16 and 18 were found at an average of 1.5% and other strains at 4.7%. This year the self-testing rate has increased more than 200,000-300,000 people, so when HPV is detected first, there is a chance that it will be cured because the body has immunity from the vaccine. And if it is found that it is cervical cancer in stage 1 quickly, there is a 100% chance of cure. But if it is found that it is already stage 2-4, the chance of cure is low.

The World Health Organization (WHO) has launched a campaign to reduce cervical cancer in women. There is a target that by 2030, 90% of children aged 15 years must receive the HPV vaccination. The HPV vaccine can be injected from 9 years old up to 55 years old, and men can get the shot. can As for cervical cancer screening, 70% and 90% of women who sound like they have cervical cancer need treatment.

For Thailand, there has already been a campaign to screen approximately 50% of cervical cancers, with women aged 30-60 years getting the test for free, and currently only 12% of the HPV vaccine has been administered. In Thailand, children between the ages of 11-12 years are vaccinated for free, so it is expected that will be able to better meet WHO’s goals through screening and vaccination Those who do not fall into the category according to their rights It may be necessary to check each woman’s rights regarding expenses according to her right to treatment from the state.


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