Serotonin and Alzheimer’s: Research Findings and Potential Treatments

2023-12-13 07:00:00

Alzheimer’s disease is a progressive neurological disease that affects the brain and causes loss of memory and other cognitive functions.

According to what was reported in the newspaper and according to “Health Day”, a recent study found that the level of the hormone serotonin was lower in the brains of those suffering from mild cognitive impairment, compared to healthy people, and they also had a higher level of amyloid beta, which is the protein associated with Alzheimer’s.

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Serotonin is known as the happiness hormone, and according to a study conducted at John Hopkins School of Medicine, levels of the hormone were up to 25% lower in those with cognitive impairment.

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The hormone decline was in areas of the brain associated with memory, problem solving, and emotion.

The researchers followed 49 people with mild cognitive impairment and 45 other healthy people, and the participants were 55 years old.

Brain scans conducted between 2009 and 2022 showed changes in brain structure, and the protein amyloid beta was forming toxic clumps on brain cells.

Mild cognitive impairment is the intermediate state between normal brain function with aging and Alzheimer’s disease.

Symptoms include: frequent forgetting recent events, difficulty finding the right word, and loss of the sense of smell.

The researchers want to conduct further research to find out the reason for the decline in serotonin levels, and to try treatments that increase hormone levels, to see if they help patients with cognitive impairment.

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