In the United States, it succeeded in treating both leukemia and HIV by transplanting cord blood (umbilical cord blood) stem cells to leukemia patients infected with human immunodeficiency virus (HIV). Photos have nothing to do with the article. /Photo = Getty Images Bank
In the United States, it succeeded in treating both leukemia and HIV by transplanting cord blood (umbilical cord blood) stem cells to a leukemia patient infected with the human immunodeficiency virus (HIV), which causes AIDS.
According to the New York Times (NYT) and Archyde.com on the 15th (local time), a team led by Dr. Yvonne Bryson from the University of California, Los Angeles (UCLA) and Dr. Deborah Persod from Johns Hopkins University attended the Conference on Retrovirus and Opportunistic Infections in Denver on the 15th (local time). announced the results.
According to the report, the research team succeeded in treating leukemia and HIV by transplanting cord blood stem cells from an HIV-resistant donor to a leukemia patient with HIV.
This patient is a middle-aged, mixed race woman who was diagnosed with HIV positive in June 2013 and received antiretroviral treatment, and was diagnosed with acute myeloid leukemia in March 2017.
In August of the same year, the patient was transplanted with stem cells from a donor with a mutation that prevents HIV from penetrating human cells.
Antiretroviral treatment was stopped 37 months after stem cell transplantation, and no HIV was detected in the blood for more than 14 months after that. Leukemia also continues to be in remission, the researchers said. ‘Remission’ refers to a state in which symptoms are relieved or disappeared.
The result of this treatment was the third case of HIV treatment with bone marrow transplantation and the first successful case for a woman, and was highly evaluated in that it was confirmed that HIV could be treated by bone marrow transplantation, which was not applied to most HIV-infected patients.
Previously, the cases of HIV treatment with adult stem cells were male, including one Caucasian and one from South America.
Among them, a white male had no HIV detection for 12 years after bone marrow transplantation until his death in 2020, and a male from South America was also treated for HIV with the same treatment in 2019.
Reporter Lee Bo-bae, Hankyung.com [email protected]
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