Study Finds Pfizer Vaccine Unaffected by Guillain-Barré Syndrome Risk; Adenovirus Vaccines Implicated

2023-10-11 11:25:00

Certain anti-Covid vaccines increase the risk of developing Guillain-Barré syndrome, says a study published at the beginning of October in the journal Neurology and relayed this Wednesday by the French health authorities. But the Pfizer vaccine, now almost exclusively used in France, is not affected, she specifies.

Pfizer not concerned

“Messenger RNA vaccines (which includes the Moderna and Pfizer vaccines, Editor’s note) do not increase the risk of Guillain-Barré syndrome, unlike adenoviral vector vaccines,” explains the National Medicines Safety Agency. (ANSM) and Health Insurance.

Isolated cases of Guillain-Barré syndrome had been associated with having been vaccinated with AstraZeneca and Janssen vaccines, known as adenovirus vaccines and used for a time in French vaccination campaigns before being abandoned in favor of RNA vaccines. messenger, namely Moderna and Pfizer.

The study relayed on Wednesday thus sought to assess this risk by retrospectively comparing the vaccination situation of the approximately 2,000 people hospitalized for this syndrome between the end of 2020 and the beginning of 2022.

A risk more than doubled

It appears that vaccination with AstraZeneca and Janssen is indeed associated with a more than doubled risk of developing Guillain-Barré syndrome. However, researchers point out that this risk is significantly higher in the event of coronavirus infection.

On the other hand, “there was no statistically significant increase in the risk of Guillain-Barré syndrome after the administration of messenger RNA vaccines,” concludes the study. “This is reassuring in a context where messenger RNA serves as the basis for booster vaccination, immediately and in the future,” she adds.

In France, in particular, it is the Pfizer vaccine which is used almost exclusively in the campaign launched this fall by the health authorities. Other countries, particularly developing countries, however, continue to widely use adenovirus vaccines, in particular AstraZeneca.

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