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The patients, who all recovered after isolation and treatment, were given trial courses of two different antiviral drugs, Brincidofovir and Tecovimat, which had previously demonstrated the potential for treating monkeypox in animals.
The team found little evidence that Brincidofovir was helpful, but by contrast, they concluded that Tecovirimat appears to shorten the duration of treatment. Symptoms of monkeypoxand thus may also reduce the amount of time infected patients are contagious.
Tecovimat is licensed in the United States and the European Union to treat monkeypox, but it has not yet been authorized by Britain’s Medicines and Healthcare products Regulatory Agency, according to the newspaper. "Daily Express".
Symptoms of monkeypox
Andmonkeypox A rare virus similar to human smallpox, first detected in Democratic Republic of the Congo In the 1970s, cases have increased in West Africa over the past decade.
Symptoms of the disease include fever, headache and rash, which begins on the face and spreads to the rest of the body.
Rodents are the main reservoir of the virus, but humans can catch monkeypox through close contact with infected people. The infection is usually mild and most people recover within a few weeks.
virus incubation
The researchers suggest dividing the stage of monkeypox infection into two periods, according to the website World Health Organization.
The first period is the invasion period (0 days and 5 days), and its signs include fever, severe headache, swollen lymph nodes, back and muscle pain, and severe weakness (loss of energy).
In the second stage, it appears Skin rash (Within 1 to 3 days after a fever), the rash develops, starting most often on the face and then spreading to other parts of the body.
The rash is most severe on the face (95 percent of cases), and on the palms of the hands and soles of the feet (75 percent).
In about 10 days, the rash develops into fluid-filled vesicles and pustules that may take weeks to disappear completely.
disease transmission
Infection occurs due to direct contact with the blood, body fluids, skin lesions, or mucous fluids of infected animals.
In Africa, cases of infection caused by handling infected monkeys, giant gambian rats or squirrels have been reported.
It is possible that eating undercooked meat from infected animals is a risk factor associated with developing chickenpox.
It can also result from transmission of the disease at the secondary level, or from one person to another through secretions or contact.
The disease is transmitted primarily through respiratory particles that take the form of droplets that usually require long periods of face-to-face contact, which exposes family members from active cases to a high risk of infection with the disease, and it is also possible for the disease to be transmitted through sexual relations or across the placenta.
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The patients, who all recovered after isolation and treatment, were given trial courses of two different antiviral drugs, Brincidofovir and Tecovimat, which had previously demonstrated the potential for treating monkeypox in animals.
The team found little evidence that Brincidofovir was helpful, but by contrast, they concluded that Tecovirimat appears to shorten the duration of treatment. Symptoms of monkeypoxand thus may also reduce the amount of time infected patients are contagious.
Tecovimat is licensed in the United States and the European Union to treat monkeypox, but it has not yet been authorized by Britain’s Medicines and Healthcare products Regulatory Agency, according to the Daily Express.
Symptoms of monkeypox
Andmonkeypox A rare virus similar to human smallpox, first detected in Democratic Republic of the Congo In the 1970s, cases have increased in West Africa over the past decade.
Symptoms of the disease include fever, headache and rash, which begins on the face and spreads to the rest of the body.
Rodents are the main reservoir of the virus, but humans can catch monkeypox through close contact with infected people. The infection is usually mild and most people recover within a few weeks.
virus incubation
The researchers suggest dividing the stage of monkeypox infection into two periods, according to the website World Health Organization.
The first period is the invasion period (0 days and 5 days), and its signs include fever, severe headache, swollen lymph nodes, back and muscle pain, and severe weakness (loss of energy).
In the second stage, it appears Skin rash (Within 1 to 3 days after a fever), the rash develops, starting most often on the face and then spreading to other parts of the body.
The rash is most severe on the face (95 percent of cases), and on the palms of the hands and soles of the feet (75 percent).
In about 10 days, the rash develops into fluid-filled vesicles and pustules that may take weeks to disappear completely.
disease transmission
Infection occurs due to direct contact with the blood, body fluids, skin lesions, or mucous fluids of infected animals.
In Africa, cases of infection caused by handling infected monkeys, giant gambian rats or squirrels have been reported.
It is possible that eating undercooked meat from infected animals is a risk factor associated with developing chickenpox.
It can also result from transmission of the disease at the secondary level, or from one person to another through secretions or contact.
The disease is transmitted primarily through respiratory particles that take the form of droplets that usually require long periods of face-to-face contact, which exposes family members from active cases to a high risk of infection with the disease, and it is also possible for the disease to be transmitted through sexual relations or across the placenta.