Supplement May Aid in Detoxifying PFAS from the Body

Fiber Supplements Show Promise in Reducing ‘Forever Chemicals’ in the Body, BU Researcher Finds

BOSTON, MA – A Boston University researcher is making headway in the fight against PFAS – per- and polyfluoroalkyl substances, often called “forever chemicals” – with a surprisingly simple potential solution: fiber supplements. Dr. Caroline Schlezinger, a research assistant professor at BU’s School of Public Health, has been investigating whether gel-forming fibers can bind to PFAS in the digestive system and help the body eliminate them.

Initial pilot studies focused on cholestyramine,a medication typically used to lower cholesterol,showed promising results in reducing PFAS levels. However, Schlezinger’s team is now expanding the research to explore more accessible options.

“We want to figure out if we’re right: Is the hypothesis correct when we are testing it in a very controlled scenario?” Schlezinger stated.

The current research involves testing seven different diets and fiber types to pinpoint the most effective formula for PFAS reduction. Schlezinger is collaborating with Chelsea Simone, an Army veteran and nurse practitioner, to address concerns specific to veterans, a population identified as potentially having higher PFAS exposure due to military base contamination.

PFAS are widespread environmental contaminants linked to various health problems, including immune deficiencies and certain cancers. The issue has gained renewed urgency following the Trump governance’s recent rollbacks on limits for PFAS in drinking water, a move schlezinger calls “not good news.” However, she notes the changes are still under review and haven’t yet taken effect.

Crucially, Schlezinger emphasizes that this research isn’t about drastically altering diets. “What is exciting about this potential intervention is its accessibility,” she explained. “It’s feasible. I bought every single supplement…on Amazon.” Psyllium, a common ingredient in metamucil, is among the gel-forming fibers being tested.While acknowledging the research is preliminary – “I don’t want to imply that you’re going to take a fiber supplement for a few months and the PFAS are gone” – Schlezinger’s work offers a potentially low-cost and readily available method for mitigating the health risks associated with these pervasive chemicals. She advises consulting a doctor before considerably increasing fiber intake.

Schlezinger herself has been personally testing oat beta-glucan for over two years,reporting positive effects on her cholesterol levels. The ongoing research aims to maximize the effectiveness of this approach and provide a viable solution for reducing PFAS body burdens.

Does the article suggest supplements are a standalone solution for PFAS detoxification, or should they be part of a wider health strategy?

Understanding PFAS: The “Forever Chemicals”

Per- and polyfluoroalkyl substances (PFAS) are a group of man-made chemicals that have gained meaningful attention due to their persistence in the surroundings and potential health effects. Frequently enough called “forever chemicals,” PFAS don’t break down easily and can accumulate in the human body over time. Exposure happens through various routes, including contaminated water, food packaging, and certain consumer products. According to research, dietary intake appears to be a major contributor to PFAS levels in the general population, due to their long half-life and bioaccumulation – even at low parts per billion (ppb) concentrations.

How PFAS Accumulate in the Body

PFAS are remarkably stable compounds. This stability is what makes them useful in many applications, but also what makes them so problematic.

Bioaccumulation: PFAS accumulate in the body over time, meaning levels increase with continued exposure.

Long Half-Life: These chemicals have a very long half-life, meaning they remain in the body for years, even decades.

Blood Levels: Average PFAS blood levels in the population are often found in the lower ppb range, a testament to widespread exposure.

Organ Affinity: PFAS tend to concentrate in organs like the liver, kidneys, and blood.

The role of Supplements in PFAS Detoxification

While complete detoxification from PFAS is a complex process, certain supplements show promise in supporting the body’s natural elimination pathways. It’s crucial to understand that supplements are not a speedy fix and should be used as part of a broader strategy to reduce exposure and support overall health.

1. Activated Carbon

Activated carbon is well-known for its ability to bind to toxins in the digestive system, preventing their absorption.

Mechanism: Activated carbon has a large surface area, allowing it to adsorb PFAS molecules.

Dosage: follow product instructions carefully. Typically, 2-4 grams are taken before meals.

Critically important Note: Activated carbon can interfere with the absorption of medications,so take it at least 2 hours apart from other drugs.

2. Chlorella

Chlorella is a single-celled green algae packed with nutrients and known for its detoxifying properties.

Binding Capacity: Studies suggest chlorella can bind to heavy metals and potentially PFAS, aiding in their removal.

Antioxidant Support: Chlorella is rich in antioxidants, which can help mitigate the oxidative stress caused by PFAS exposure.

Dosage: 1-3 grams daily is a common starting point.

3. Sulforaphane

Found in cruciferous vegetables like broccoli and kale, sulforaphane is a potent antioxidant and detoxification aid.

Phase II detoxification: Sulforaphane supports Phase II detoxification pathways in the liver, helping to convert toxins into forms that can be more easily excreted.

Bioavailability: Consider a sulforaphane supplement with myrosinase for enhanced absorption.

Dosage: Varies depending on the product; follow label instructions.

4. N-Acetyl Cysteine (NAC)

NAC is a precursor to glutathione, a master antioxidant and crucial component of the body’s detoxification system.

Glutathione Production: NAC helps boost glutathione levels, enhancing the liver’s ability to process and eliminate toxins.

Liver Support: Supports overall liver health, which is vital for detoxification.

Dosage: 600-1800mg daily, divided into doses.

5. Calcium Bentonite Clay

This type of clay possesses strong adsorptive properties.

Adsorption: Bentonite clay can bind to toxins in the digestive tract,preventing their absorption.

Mineral Rich: Provides essential minerals.

Dosage: 1-2 tablespoons mixed with water daily. Ensure it’s a food-grade clay.

Dietary and Lifestyle Strategies to Minimize PFAS Exposure

Supplements are most effective when combined with efforts to reduce PFAS exposure and support the body’s natural detoxification processes.

Water Filtration: Invest in a high-quality water filter certified to remove PFAS.Reverse osmosis and activated carbon filters are effective options.

Food Choices: Limit consumption of processed foods, fast food, and non-stick cookware. Opt for organic produce when possible.

Avoid Stain-Resistant Products: Reduce exposure to products treated with PFAS, such as stain-resistant carpets and clothing.

Hydration: Drink plenty of water to support kidney function and toxin elimination.

Support Liver Health: Consume a diet rich in fruits, vegetables, and healthy fats to support liver function.

Regular Exercise: Physical activity promotes circulation and helps the body eliminate toxins through sweat.

Critically important Considerations & Disclaimer

Consult a Healthcare Professional: Before starting any new supplement regimen, it’s essential to consult with a qualified healthcare professional,