California’s CalRx Generic Insulin Rollout Faces Slow Start at Pharmacies

California’s state-backed generic drug initiative, CalRx, faces a slow start at retail pharmacies despite offering long-acting insulin glargine pens for a recommended price of $11 each. Governor Gavin Newsom introduced … Read More

Combination Therapy for Relapsed Aggressive B Cell Lymphoma Shows Encouraging Preliminary Results

In a phase 1 clinical trial published this week in Nature Medicine, the combination of englumafusp alfa and glofitamab demonstrated manageable safety and preliminary efficacy in patients with relapsed or … Read More

COMPASS: Pan-Cancer Foundation Model Predicts Immunotherapy Response

Researchers have developed COMPASS, a pan-cancer foundation model that predicts immunotherapy response, across cancer types and treatments, from bulk tumor transcriptomes. In Plain English: The Clinical Takeaway Predictive Accuracy: COMPASS … Read More

CAR T Cell Therapy in Smoldering Myeloma: Balancing Deep Responses with High Toxicity Risks

Researchers have successfully utilized Chimeric Antigen Receptor (CAR) T cell therapy to target smoldering multiple myeloma, an asymptomatic precursor to bone marrow cancer. Published in Nature Medicine this June, the … Read More

Breakthrough Vaccine Shows Safety and Efficacy Against Lassa and Rabies in Human Trial

A first-in-human phase 1 trial published this week in Nature Medicine found an experimental vaccine combining inactivated rabies virus and Lassa fever antigens—with an adjuvant to boost immune response—to be … Read More