Unlocking the Potential of Regenerative Medicine: Insights from Dr. Patricio Centurión

2024-04-13 12:00:00

Is it possible to regenerate tissues? Advances in medical science open a light of hope with regenerative medicine. Dr. Patricio Centurión explains this innovative system to us.

What exactly is regenerative medicine?

Regenerative medicine is an innovative transversal branch. Transversal in the sense that it covers almost all specialties. Each specialty is dedicated to a type of organ, tissue, and this medicine allows the various organs and tissues to regenerate. Something that started very limited, to a topic of wounds in plastic surgery, now we are using it to generate other tissues.

Did it always have those origins or did it expand over the years?

It has recently expanded, because we have found various sources of stem cells. Before they were difficult to access. The most innovative were those from bone marrow, which is through puncture of the bone, and fat. The big difference is that from the same volume of stem cells, you get one cell from the bone marrow versus 500 that you get from fat.

Patricio Centurión: “We use the patient’s own cells” [entrevista completa]

What’s new?

Before, bone marrow was very popular to use, but now we are entering the most important source, which is the fat in the subcutaneous cellular tissue where the greatest number of stem cells is found, most of them being of great and high quality. .

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Tell us about stem cells. What exactly are they and what are they for?

Stem cells are of various types. There are stem cells that can only divide in one tissue, and that exists in all organs: in the pancreas, the lung…, because, permanently, those old cells are dying and new ones are generated. But there is a bank of stem cells that can be divided into various tissues: those are the multipotential mesenchymal cells, which allow these cells to differentiate into cartilage, tendon, ligaments, muscle, nerves… and those are the ones that are found under the fat.

How does it work?

Stem cells have been used all over the world for many years, but what changes it is how I harvest them. Under the skin there is a regenerative orchestra so to speak where the conductor is the mother cell that has 50 musicians; that you have to try to transplant and modify them, that they are not dependent on fat, but rather a system of their own, where we have the 50 musicians and the orchestra director who, when we transplant it to any organ that is damaged, that organ sends SOS signals . The organism is going to produce, among all those 50 musicians directed by the stem cell, it is going to regenerate and restore those tissues, equal to the original.

Dr Patricio Centurión.

In which patients is this treatment applied?

We started in Brazil, where we have done a lot of research, where we continue to do research; We have already started as a pattern for complex injuries: for diabetic feet, orthopedic problems (knees, shoulders, hips), intervertebral discs. Also for those who have interdiscal herniations and obviously we are treating patients who have spinal cord injuries.

Tell us about the One Step technique, you created it…

Yes. I have been studying this topic of regenerative medicine since I was a general surgeon in Brazil. My general surgery professor was a researcher, and he was the one who led me to this path of regenerating. The great advantage of the One Step technique is that we use, first of all, the patient’s own cells. Secondly, we do not use a laboratory to process those cells. Every time the material enters, as is the case in other countries, when it enters the laboratory to be processed, they are adding reenzymes and chemical reagents, eliminating the audience, they are going to kill many musicians, and they only concentrate on the orchestra conductors. Instead, we are preserving all the elements, and that is why we have responses with a single application and through injections.

Mother cells. (Photo: Pixabay)

What is stem cell research like in Peru? How are we compared to Brazil?

In Brazil we have many cities with various universities and scientific societies that are always asking for my support to be able to work and I thank all my Brazilian colleagues. Here in Peru I am a professor at the Ricardo Palma University, where the Biomedical Sciences Research Institute has supported my work for some years, because it is allowing me to do some of that research outside my country.

What are you offering?

Treatments for joint problems, various joints, intervertebral disc problems, neurological problems at the level of the spine. We are going to move forward now to try to look for another type such as, for example, Parkinson’s, we are coordinating a protocol, because we must create not only the harvesting technique, but also how to get there and what dose to apply to each patient.

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