Vascularization of Bioprinted Organs: The Next Step Before Transplantation | Science and Avenir

2023-11-26 20:00:00

Next step before their transplantation: ensuring the vascularization of the bioprinted organs.

This article comes from the magazine Les Indispensables de Sciences et Avenir n°215 dated October/December 2023.

Mimic human tissue or an organ as best as possible: this is the challenge of bioimpression 3D, through which researchers can test the effect of a drug or radiotherapy on organoids, simplified models of the liver, skin, etc. To form this tissue, a laser detaches, one by one, nano-droplets of cells in culture.

Necessary blood circulation

But to compensate for the shortage of human organs and produce transplantable structures, they would need to be irrigated by blood circulation which nourishes and oxygenates them. Devices capable of initiating this circulation are currently being tested. Once printed, the fabric is connected to one of them, which establishes a continuous flow in the vessels. Ultimately, this technology would allow the formation of the network of capillaries, the finest vessels, inside the organ or tissue, allowing their transplantation.

Find this article on sciencesetavenir.fr

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