Dr. Anan reveals research from China. Covid-19 virus found can infect into T cells. This may be a mechanism explaining why in many severely ill patients have reduced white blood cell count.
Today (17 April 65) Dr. Anan Jongkaewwattana, a researcher in virology Biotech posted a message via Facebook Anan Jongkaewwattana about the Covid-19 virus, stating that
“One study published by a research team from China indicates that SARS-CoV-2 virus can infect T cells and that virus-infected cells are induced. To destroy yourself and eventually die. This may be the mechanism that explains why in many severe coronavirus patients their white blood cell count is reduced. (Lymphopenia)
This research has shown quite clear experimental results that The virus can infect T cells. Especially white blood cells that are in a state that is stimulated and ready to divide (activated T cells) by the mechanism of entering cells is different from normal cells. Because viruses do not use the ACE2 protein as a receptor protein. Instead, it appears to have used another protein called LFA-1. The research has not detailed whether the virus directly binds to the spike protein, or through mechanisms that do not directly use the spike protein.
An important point that may need to be clear is the similarities and differences between the HIV virus and the SARS-CoV-2 virus. According to the data in this study, SARS-CoV-2 virus can infect both CD4 T cells, but The difference is that SARS-CoV-2 becomes infected and causes cell death relatively quickly, and the data appears to be getting very little of the new virus out of the infected cells. This could be that T cells are not suitable hosts like respiratory cells or lung cells that can produce large amounts of new virus particles.
But for HIV, CD4 T cells are used as the main plant for the virus, and the number of plants can be increased endlessly. Because a virus can infuse its genetic material with the host’s DNA, when the cell divides, the genetic material of the infiltrated virus is also attached. Become a factory that creates viruses forever. There is almost no way to get HIV out of the patient’s body at all.
Since SARS-CoV-2 is infected, the host (T cell) dies, does not divide, and the viral RNA strand does not bind to the cell’s DNA, there is concern that SARS-CoV-2 will cause acquired immunodeficiency virus (AIDS). Like HIV, it’s impossible. https://www.nature.com/articles/s41392-022-00919-x”
AFP image file