2023-08-07 20:30:00
Despite the report that the corona vaccine is relatively safe, it appears that the actual rheumatism patients have a greater adverse effect than the flu vaccine.
This is because the adverse reaction rate and disease activation rate, that is, the risk of rheumatoid disease recurrence, were more than 10 times higher than when receiving influenza vaccine.
A study comparing the adverse reactions between the corona vaccine and the influenza vaccine came out.
On the 14th, the Journal of Korean Medical Science, an international academic journal of the Korean Medical Association, will publish the results of a comparative analysis of the effects of corona vaccine and influenza vaccine on rheumatoid patients.
Despite the current endemic trend, as the number of corona patients continues to increase, the demand for corona vaccines, including diagnostic kits, is gradually increasing.
During the corona pandemic, it was recommended that patients with autoimmune diseases, such as rheumatism patients, benefit from vaccination, but the reality is that there is insufficient evidence on the actual impact on these patients.
In particular, as the corona vaccine is approved and administered at an unprecedentedly fast speed, doubts about safety still continue.
This is also the background that the research team led by Professor Kim Hyun-ah of Ajou University Medical School conducted a study on rheumatism patients who actually received the corona vaccine in Korea.
It is to compare the impact of the corona vaccine on patients compared to the influenza vaccine, which many patients are already receiving, to identify the risks.
Accordingly, the research team compared and analyzed the difference in clinical prognosis when vaccinated with the influenza vaccine for 601 rheumatism patients who were vaccinated with the corona vaccine.
Comparative analysis of corona vaccine and influenza vaccine adverse reactions
As a result of the analysis, 42.4% of 601 patients completed the first vaccination and 56.9% received additional vaccination.
The first vaccination was 61.4% with the Pfizer vaccine, and additional vaccinations were also confirmed at 83.3%, Pfizer and Modena at 16.4%.
When comparing the adverse reactions after vaccination, it was found that 52.2% of the rheumatism patients who received the corona vaccine had an adverse reaction. This is quite high compared to only 5.8% after receiving the influenza vaccine.
In terms of adverse reaction rates, muscle pain was the most common at 27.5%, followed by sudden fatigue at 20.8%, headache at 18.1%, and fever at 17.5%. However, there was no significant difference among vaccine manufacturers.
In addition, most of the patients passed without problems about adverse reactions after influenza vaccination, but 7.5% of patients visited an outpatient clinic due to adverse reactions to the corona vaccine, and 2.2% were hospitalized in the emergency room.
The rate of disease activation, i.e., the re-activation of well-managed rheumatic diseases, was also much higher with the corona vaccine.
This is because the rate of activation of the disease after receiving the corona vaccine was 16.2%, which was more than 10 times higher than the influenza vaccine (1.4%).
In particular, 80 % of patients were counted as 67.2 % of patients found a medical institution as the disease was activated within 3 days after corona vaccine.
The research team said, “As a result of the study, rheumatism patients who received the corona vaccine had an overwhelmingly higher rate of disease activation, a very important problem, compared to the influenza vaccine.”
“It is meaningful in that it is the first study to compare adverse reactions and disease activation rates between influenza and corona vaccinations,” he said. .
1691442803
#Corona #vaccine #dangerous #flu #vaccine #rheumatic #patients