Controversial Plastic Trachea Transplant: The Rise and Fall of a Renowned Researcher

2023-06-21 16:58:05

The researcher achieved international fame in 2011 by performing the world’s first artificial plastic trachea transplant, to fill it with the patient’s stem cells.

This experimental procedure was initially hailed as a major step forward in the field of regenerative medicine, before being criticized for not being well-founded.

On Wednesday, the Stockholm Court of Appeal concluded that two of the three patients were not in a sufficiently severe condition at the time of surgery, and “would have survived for a long time otherwise.”

The court added that the third patient was in an emergency condition, but that “the measure, however, was not justified.”

Macchiarini is a former visiting researcher at the Karolinska Institute in Stockholm, from which the association responsible for awarding the Nobel Prize for Medicine descends, and he operated on 8 people between 2011 and 2014, 3 of them in Sweden and 5 in Russia.

Among Macchiarini’s patients, 64, only one survived, after the artificial windpipe that the doctor designed and implanted during an operation in Russia in 2014 was removed from his body.

The three patients who were treated in Sweden died, without establishing a direct link between their deaths and the surgeries.

Initially, the surgeon was found guilty of inflicting “bodily harm” on a patient, the court concluded that his surgical interventions were contrary to “proven knowledge and experience”, and the charges relating to the two other patients were dropped.

Macchiarini was convicted of scientific fraud by an external committee, and dismissed from Karolinska Institutet in 2016.

In 2018, the scientific magazine “The Lancet” withdrew two articles signed by Al-Jarrah, which were published in 2011 and 2012.

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