[이데일리 이순용 기자] The research result that oral lactic acid bacteria inhibits respiratory and intestinal infection viruses was published in the international journal Probiotics and Antimicrobial Proteins. This is the “in vitro antiviral effect of oral probiotic oraCMS1 on respiratory virus and rotavirus”, a study conducted by Ora Pharm, a company specializing in oral lactic acid bacteria, for 6 months from May 2020.
The virus used in this study is a representative virus that causes respiratory infections in Korea from autumn to winter. Influenza A virus (H1N1), also called influenza A virus (H1N1), is a rotavirus (RVA) transmitted by the oral route, causing enteritis and the most common cause of diarrhea in infants and children. The test method was conducted according to ASTM (American Society for Testing and Materials) E1052-20 test method. The purpose of this study was to evaluate the efficacy of the sterile supernatant of oraCMS1 against respiratory syncytial virus, influenza A virus, and rotavirus A.
The test was conducted by mixing the sterile supernatant of oral lactic acid bacterium oraCMS1 with each virus culture, contacting them for 1 hour, 2 hours, and 4 hours, and then checking the virus activity. Virus activity was measured by 50% tissue culture infectivity assay after virus infection in host cells. As a result of the test, the respiratory syncytial virus was inactivated up to 99.0% after 1 hour and up to 99.9% after 2 hours and 4 hours, and for influenza A virus and rotavirus A up to 99.9% and 99.0% after 2 hours, respectively. appeared to be inactive.
“This study is the first study in Korea to confirm the efficacy of oral lactobacilli against the virus, and this study suggests that oral probiotics can help reduce the risk of respiratory and intestinal infections,” said an official from Orapam. Human application tests are needed to verify efficacy.”
Ora Farm is a specialized R&D-focused company that pioneered functional lactic acid bacteria called oral lactic acid bacteria in the domestic lactobacillus market centered on intestinal lactic acid bacteria. After research to find Korean probiotics suitable for Koreans without relying on foreign strains, the oral lactic acid bacteria strain oraCMS1 was isolated and identified from the mouths of Korean children. Oral lactic acid bacteria products using oraCMS1 include ‘Auratix Denti’ and ‘Auratix Kids’ for children.
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