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Ozempic & Wegovy: Benefits & Side Effects Explained

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Ozempic and Wegovy: Vision Loss Concerns Emerge Amidst Weight Loss Boom

The weight loss drugs Ozempic and Wegovy, both containing semaglutide, are now available by prescription in New Zealand as of this week. Initially introduced in the U.S. in 2017 as a diabetes treatment, semaglutide has rapidly gained recognition for its critically important effects on weight loss.However, alongside their benefits, these medications come with potential risks, including vision-related complications.

The Promise and Peril of Semaglutide

Wegovy is now available for individuals over 12; however, the estimated monthly cost of $500 may be prohibitive for many of the 65% of New Zealanders classified as overweight or obese. While semaglutide drugs offer transformative potential in managing obesity,type 2 diabetes,and potentially conditions like alzheimer’s,addiction,and depression,concerns about side effects,particularly vision loss,demand attention.

Grace Wade, a health reporter for New Scientist, highlighted a specific concern: non-arteritic anterior ischemic optic neuropathy. This condition arises from insufficient blood flow to the optic nerve,potentially leading to sudden and permanent vision impairment,usually in one eye. The vision loss is frequently enough described as cloudiness rather than total blindness.

A 2024 study revealed that individuals using semaglutides for diabetes were 4.3 times more likely to develop this condition, while those using it for weight loss faced a 7.6 times higher risk compared to

What is the primary difference between Ozempic and Wegovy regarding FDA approval and intended use?

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Ozempic & Wegovy: Benefits & Side Effects Explained – Weight Loss Medications

Ozempic & Wegovy: Benefits & Side Effects Explained

What are Ozempic and Wegovy?

Ozempic (semaglutide) and Wegovy (also semaglutide) are injectable medications initially developed for managing type 2 diabetes. Both drugs belong to a class of medications called GLP-1 receptor agonists. They work by mimicking the effects of the naturally occurring GLP-1 hormone, which regulates appetite and blood sugar levels. While Ozempic is approved for diabetes treatment, Wegovy is specifically approved at a higher dosage for weight management in adults with obesity or who are overweight with at least one weight-related medical condition.

Key Differences: Ozempic vs. Wegovy

The primary difference lies in the dosage and intended use. Wegovy delivers a higher dose of semaglutide than Ozempic, making it more effective for weight loss. Using Ozempic *off-label* for weight loss is common,but Wegovy is the FDA-approved option for this purpose. Understanding this distinction is crucial when discussing these medications with your healthcare provider.

Feature Ozempic Wegovy
Active Ingredient Semaglutide Semaglutide
FDA Approved For Type 2 Diabetes Weight Management (Obesity/Overweight + Comorbidities)
Maximum Dosage 2.4mg weekly 2.4mg weekly
Typical weight Loss Variable, frequently enough less than Wegovy Around 15% of initial body weight

Benefits of Ozempic & Wegovy

  • Significant Weight Loss: Clinical trials demonstrate ample weight loss with Wegovy, often exceeding results from lifestyle interventions alone. Ozempic can also contribute to weight loss, though typically to a lesser extent.
  • Improved Blood Sugar Control: For individuals with type 2 diabetes,Ozempic effectively lowers blood glucose levels.
  • Reduced Cardiovascular Risk: Studies suggest GLP-1 receptor agonists may reduce the risk of major cardiovascular events in people with type 2 diabetes.
  • Appetite Suppression: These medications work by slowing gastric emptying and increasing feelings of fullness, leading to reduced calorie intake.
  • Potential for Long-Term Management: When combined with lifestyle changes, Ozempic and Wegovy can be part of a long-term weight management strategy.

Common Side Effects

Like all medications, Ozempic and Wegovy can cause side effects. Most are mild to moderate and tend to subside over time. It’s important to discuss any concerns with your doctor.

  • Gastrointestinal Issues: Nausea, vomiting, diarrhea, constipation, and abdominal pain are the most frequently reported side effects.
  • Injection Site Reactions: Redness, swelling, or pain at the injection site.
  • Headache: Some individuals experience headaches, especially when starting the medication.
  • Fatigue: Feeling tired or weak.

Serious side Effects (Rare)

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