Revolutionary Drug for Tooth Regeneration: Japanese Researchers Make Breakthrough

2023-07-04 23:22:08

A team of Japanese researchers is developing a drug that apparently could regenerate and grow new teeth.

The drug would be the first of its kind in the world. It has already been tested on animals, giving positive results, due to the growth of “third generation” teeth, slogan German wave.

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The team led by Katsu Takahashi, principal investigator and director of the Department of Dentistry and Oral Surgery at the Kitano Hospital of the Institute of Medical Research in the city of Osaka, estimated that the drug can be developed and ready to go on the market in 2030.

“I’ve been working on this since I was a graduate student. I was sure that I would be able to make it happen“, commented the researcher quoted by the Japanese newspaper The Mainichi.

This medicine could be of great help to those who suffer from anodontiaa congenital condition that describes the absence of one or more primary or permanent teeth and affects about 1% of the population.

Protein USAG-1

Takahashi focused on the investigation of the USAG-1 protein, synthesized by the gene, limits tooth growth. The researcher understood that by blocking the action of this protein, more teeth could grow. This is why he decided to create a neutralizing antibody drug.

In 2021 and as detailed in an article, the results of taking the drug in rats was the growth of new teeth.

To get to the next stage, The researchers intend to use the drug for boys and girls between the ages of 2 and 6 who present anodontia.

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