2023-04-27 14:57:52
Find out how researchers have identified an innovative and effective way to fight anxiety by manipulating the expression of certain genes.
Hope for anxious people
Faced with the growing increase in cases of anxiety in the world, it is more than urgent to find new treatments. Current drugs are not effective enough for many patients, and access to psychologists remains complicated. It is in this context that researchers from the universities of Bristol and Exeter have discovered a new avenue for the development of drugs against anxiety. This breakthrough could potentially change the lives of millions of people suffering from this condition.
The key: gene expression
Scientists have found that boosting certain genes that naturally reduce anxiety may be the answer. By manipulating these genes in mice, they obtained promising results. The discovery of this new treatment method could revolutionize the way we approach and treat anxiety.
The miRNA miR483-5p: a hope to fight against anxiety
The research focused on the use of the miRNA miR483-5p, which acts at the level of the amygdala, a region of the brain involved in the regulation of emotions and therefore linked to anxiety. By manipulating this miRNA in mice, the researchers discovered that it acts on the Pgap2 gene, which leads to changes in brain neuronal morphology and behavior associated with anxiety. Thus, miR483-5p is able to block the effects of amygdala-induced stress, inhibiting anxiety.
If it happens naturally, why do we suffer from anxiety?
One might wonder why some people suffer from anxiety if this natural mechanism exists. The answer lies in the fact that this process only works at reduced levels of stress. When stress is caused by an acute traumatic event or persists for a long time, natural mechanisms are no longer sufficient.
This is where therapy and, in some cases, anti-anxiety medications come into play. If a drug capable of increasing the effect of this miRNA were developed, it might be possible to counteract anxiety even when the stress is greater.
A major breakthrough in the fight against anxiety
This discovery paves the way for new anti-anxiety medications. Nevertheless, it should not be forgotten that psychological therapy remains essential. It is crucial to continue to fight so that all people can access psychological care, regardless of their economic resources. Thanks to this scientific advance, we can hope for a significant improvement in the management of anxiety, for a better quality of life for the millions of people affected. As we eagerly await the development of these new treatments, we must continue to support access to psychological therapy for all.
My name is Sarah, and I’m an editor at 180back.com. Specializing in the areas of health, wellness and music, I enthusiastically share my knowledge, advice and discoveries to inspire and help our readers lead balanced and fulfilling lives.
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