2023-04-19 14:09:08
SAPA (pollen-food allergy syndrome) induced by the ingestion of raw apple is one of the most common oral syndromes. In effect, 70% of people allergic to this fruit are also allergic to birch pollen by cross-allergy between allergens of the PR10 family.
This phenomenon also concerns other foods such as hazelnuts, carrots, walnuts, celery, stone fruits, chestnuts, pears, kiwis and peanuts. The great particularity of the allergens of the PR10 family, which are more often present in the pulp, is that they are destroyed by cooking and digestion. Patients can then eat the cooked apple (pie, compote, jam). After consumption of raw apple, the symptoms are often moderate (lip, mouth, pharyngeal or ear pruritus associated with slight circumoral oedema).
With other allergenic families (see below), cross-reactions between pollen and food are more at risk of anaphylaxis from the outset. But beware: in recent years, there have been reports rare anaphylactic reactions to PR10 favored by the concomitant intake of NSAIDs, beta-blockers, ACE inhibitors, or by post-prandial effort. Between 2011 and 2022, 30 cases were reported in children under 18 by the allergy vigilance network (RAV), mainly responsible for soy, hazelnut and kiwi (and sport as a contributing factor).
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#Pollen #allergy
