2023-10-18 11:04:00
After being vaccinated, it is not uncommon to have redness, pain, or swelling in the stung area. Depending on the vaccine and the individual, other symptoms may appear:
These are generally temporary and disappear on their own after a few hours or even days. Some vaccines have a greater risk of side effects than others. This is the case for vaccines aimed at to protect against Covid-19.
Faced with numerous reports of adverse effects following vaccination against Covid-19, the ANSM (National Agency for the Safety of Medicines and Health Products) has developed monitoring of “cases of adverse reactions to Covid-19 vaccines“. According to their latest figures from March 9, 2023, more than 156,476,800 injections were given with the different vaccines.
Among the reported cases of side effects, the organization estimates that nearly 75% of cases are “non-serious”. The most serious adverse effects monitored by the ANSM include: deafness, pancreatitis and heart rhythm disorders. The ANSM specifies: “a declared case corresponds to a vaccinated person in whom the occurrence of one or more adverse events after administration of a vaccine gave rise to a pharmacovigilance declaration”. Thus, these effects remain rare, most of the symptoms being the same as for most vaccines. Moreover, a study has just revealed that experiencing these mild symptoms would be positivethis would show greater immunity to the virus. The study, carried out by researchers at the University of California (United States) was published on October 6, 2023 in the American journal MedRxiv.
Researchers followed the vaccination schedule of 364 adults
For this study, the authors followed 364 adult participants to the Building Optimal Antibodies Study16, a large observational study designed to identify psychosocial, behavioral and biological predictors of immune responses to vaccination against Covid-19. The volunteers were not vaccinated and were completed their two doses of the vaccine independently, during the study. The researchers tracked this through patients’ medical records.
Scientists have measured their presence of antibodies before the vaccinebut also after one month and six months. “Neutralizing antibodies against SARS-CoV-2 were measured via a pseudovirus test 1 and 6 months after vaccination“, detail the authors. The symptoms were also recorded through questionnaires. The researchers were informed of the two dates of participants’ vaccine injections thanks to their medical data. So, on the evening of the two injections, they received a questionnaire to complete and this during a duration of six days. In it, they had to check if they had experienced any of the symptoms mentioned during the day. The questionnaires included various signs such as: headache, vomiting, stomach ache, fever, or arm pain. The scientists then sought to compare the symptoms experienced with the level of antibodies.
Antibodies: up to 200% higher in people with symptoms
The results showed that people who had the most symptoms after the vaccine had a higher level of antibodies. “People who reported having chills, fatigue, malaise or headache after the second dose of a SARS-CoV-2 vaccine had subsequently a 140 to 160% higher level of neutralizing antibodies to that of people who had not declared these symptoms, both 1 and 6 months later”, detail the authors.
Moreover, the amount of symptoms was also associated with the amount of antibodies. Thus, the more different symptoms a person had, the more antibodies she had. Individuals who declared 7 distinct symptoms therefore had almost 200% antibody levels more than those with no symptoms. “The more people reported symptoms, the higher their antibody level was“, shares Aric Prather, clinical psychologist at the University of California at San Francisco and lead author of the study. Certain specific side effects were also more associated with a strong immune response. This was the case for fatigue, fever and heart rate.
Vaccine against covid-19: it remains effective even without symptoms
However, don’t panic if you have not had any side effects after your vaccine. If this study insists that having symptoms after the vaccine strengthens immunity to the virusthis does not mean that people who do not feel no side effects are not protected.
“Many people who described mild or no symptoms and had high amounts of neutralizing antibodies“, reassures author Aric Prather. Thus, the antibodies are present in smaller quantities, but they are still there and in sufficient quantity to be protected against Covid-19.
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